CARDIOVASCULAR RISK FACTOR
Clinical trials for CARDIOVASCULAR RISK FACTOR explained in plain language.
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Could a simple drug switch protect the hearts of people with HIV?
Disease control CompletedThis study looked at whether switching to a specific HIV medication called doravirine could be better for heart health compared to other common HIV drugs. It involved 26 adults with stable, treated HIV and high cholesterol. Researchers measured cholesterol function and markers li…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: EARLY_PHASE1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Can a lifestyle program fight weight gain and stress in Hard-Hit neighborhoods?
Disease control CompletedThis study looked at how a year-long diabetes prevention program affected weight, heart health, and stress levels in 15 adults from socioeconomically disadvantaged communities. Researchers measured changes in body weight, cardiovascular risk factors, and psychological stress to s…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Could a Two-Week drink improve your heart and mind?
Disease control CompletedThis small study tested whether drinking a ketone supplement for two weeks could improve heart and brain health in older adults. Eleven participants aged 50-75 tried both the ketone drink and a placebo for two weeks each. Researchers measured blood pressure, blood vessel function…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Stand up for your health: simple swap cuts blood sugar spikes
Disease control CompletedThis study tested whether replacing sitting time with standing and light walking could improve daily blood sugar control. It involved 18 South Asian adults with overweight or obesity who normally sat a lot. Participants tried two different 4-day routines: one with lots of sitting…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Bedfordshire • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Sleep therapy may shield PTSD hearts
Disease control CompletedThis study investigated whether treating insomnia could reduce the higher risk of heart disease seen in people with PTSD. Researchers enrolled 140 adults with both PTSD and insomnia. They tested if an 8-week sleep therapy program could improve key markers of heart health, like bl…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Southern twist on mediterranean diet battles weight watchers in Head-to-Head trial
Disease control CompletedThis study tested a new 2-year weight loss program called 'Med-South,' which adapts a Mediterranean-style diet for Southern U.S. preferences. Researchers compared it directly to the popular WW (Weight Watchers) program. The goal was to see which approach helped 360 adults with ob…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Could simple stretching protect moms and babies from pregnancy risks?
Prevention CompletedThis study tested if a stretching program is better than standard exercise advice for lowering heart and blood pressure risks in pregnant women with obesity. It involved 224 women from 27 to 37 weeks of pregnancy. The goal was to see if stretching could help prevent serious pregn…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Prevention
Last updated Mar 31, 2026 12:12 UTC
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Can a year of online coaching get inactive adults moving to prevent heart disease?
Prevention CompletedThis study tested whether a one-year online program could help inactive adults at risk for heart disease get more exercise. The program included weekly coaching sessions, remote support, and a wearable activity tracker. Researchers compared this intensive program to a simpler app…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated Mar 23, 2026 15:21 UTC
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Is orange juice really better than soda? science weighs in
Knowledge-focused CompletedThis study aimed to understand if drinking orange juice has different effects on heart and diabetes risk factors compared to sugary drinks like soda. Researchers had 56 normal-weight and overweight adults drink either orange juice or a sugar-sweetened beverage daily for four week…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Teen lifestyle choices cast long shadow on adult heart risk
Knowledge-focused CompletedThis study followed up with 72 young adults who were part of a large European health survey as teenagers 10 years ago. Researchers aimed to understand how diet, physical activity, and other lifestyle factors during adolescence influence the risk of developing heart problems in ea…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Can a common nutrient hurt your heart? small study investigates
Knowledge-focused CompletedThis study aimed to understand if taking a choline supplement for a short time could harm blood vessel function in healthy adults. Researchers gave 20 participants either choline or a placebo for five days and measured how well their arteries worked. The goal was to gather basic …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Could your fitness level protect your gums?
Knowledge-focused CompletedThis study looked back at health records to see if there's a link between a person's physical fitness, body weight, and the health of their gums. Researchers analyzed data from 61 adults, checking their gum health, activity levels, and body measurements. The goal was to understan…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: Universidad Rey Juan Carlos • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Eggs vs. pills: the surprising heart health difference?
Knowledge-focused CompletedThis study aimed to understand if the body processes choline—a nutrient needed for health—differently when it comes from eggs versus from supplements. Researchers wanted to see if these different sources changed the level of a blood compound (TMAO) linked to heart disease risk. T…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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One salty meal could strain your heart more if You're black, study suggests
Knowledge-focused CompletedThis study aimed to understand why Black individuals are more prone to high blood pressure and heart problems from eating too much salt. Researchers compared how a single high-salt meal affected blood pressure and blood vessel function in healthy Black and White adults. They meas…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists test if harder workouts curb appetite
Knowledge-focused CompletedThis study aimed to understand how different workout intensities affect a hormone called ghrelin, which controls hunger and metabolism. Researchers compared high and low-intensity exercise in 40 lean and obese adults, some with prediabetes, to see how it changed hormone levels, a…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:42 UTC