CARDIOVASCULAR RISK FACTOR
Clinical trials for CARDIOVASCULAR RISK FACTOR explained in plain language.
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HIV drug switch may protect hearts: small study hints at benefit
Disease control CompletedThis early-phase study tested whether switching HIV medications to doravirine (with emtricitabine/tenofovir alafenamide) could improve cholesterol and reduce early signs of heart disease in 26 people with well-controlled HIV. Participants had stable HIV and high cholesterol. The …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: EARLY_PHASE1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated May 17, 2026 04:23 UTC
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Southern-style mediterranean diet takes on weight watchers in weight loss showdown
Disease control CompletedThis study tested a new weight loss program called Med-South, which adapts the Mediterranean diet for Southern tastes, against the popular WW (Weight Watchers) program. Over 2 years, 360 adults with obesity were randomly assigned to one of the two programs. Researchers measured w…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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Short walks beat sitting: new hope for south asian heart health
Disease control CompletedThis study looked at whether taking short, regular walks during long periods of sitting can lower blood sugar and cholesterol after meals—key risk factors for diabetes and heart disease. Researchers compared normal-weight and overweight/obese South Asian adults who sit at least 7…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Bedfordshire • Aim: Disease control
Last updated Apr 26, 2026 19:35 UTC
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Step up to health: online program aims to prevent heart disease
Prevention CompletedThis study tested a year-long online program to help adults aged 40-70 who are at risk for heart disease become more active. Participants received a fitness tracker, online coaching, and educational sessions. The goal was to see if this approach could increase daily steps and hel…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated May 17, 2026 04:13 UTC
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Stretching may lower heart risks in obese pregnant women
Symptom relief CompletedThis study looked at whether a stretching routine could help reduce heart-related health risks in pregnant women with obesity during late pregnancy. 224 women participated from week 27 to week 37 of pregnancy. The stretching group was compared to a group doing moderate to vigorou…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated May 17, 2026 04:12 UTC
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Ketone drink shows promise for heart and brain health
Symptom relief CompletedThis study tested whether drinking a ketone supplement three times a day for two weeks could improve blood vessel health and thinking skills in adults aged 50-75. Eleven participants each tried the ketone drink and a placebo (flavored water) in random order, with a two-week break…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Eggs vs. pills: which choline source raises heart risk marker more?
Knowledge-focused CompletedThis study looked at how choline from eggs or supplements changes levels of TMAO, a compound tied to higher heart disease risk. Researchers compared 86 adults who ate eggs or took choline pills for 28 days. The goal was to see if the source of choline matters for TMAO production …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 04:15 UTC
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Sleep therapy may protect hearts of PTSD patients
Knowledge-focused CompletedThis study looked at whether treating insomnia could reduce the risk of heart disease in 140 adults aged 40-59 with PTSD. Researchers measured blood pressure, sleep quality, and other heart risk factors before and after insomnia treatment. The goal was to understand the link betw…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 17, 2026 04:15 UTC
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Tiny plaques, big clues: study probes hidden heart risks
Knowledge-focused CompletedThis study looked at 90 people with low or medium heart risk to see if tiny, non-blocking plaques in the heart arteries affect how blood clots and how blood vessels work. Participants had a special CT scan to find these small plaques, and their blood was tested for clotting activ…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: University of Sao Paulo • Aim: Knowledge-focused
Last updated May 17, 2026 04:13 UTC
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One salty meal could reveal why black americans face higher blood pressure risks
Knowledge-focused CompletedThis study looked at whether a single high-salt meal affects blood pressure and blood vessel function differently in Black versus white adults. About 71 healthy people aged 19-40 ate both a high-salt and a low-salt tomato soup meal on separate days. Researchers measured blood pre…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated May 17, 2026 04:12 UTC
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Could your workout routine protect your gums?
Knowledge-focused CompletedThis study looked at 61 adults to see if physical fitness, diet, and body measurements like weight and waist size are linked to gum disease. Researchers reviewed dental records and questionnaires from a previous study. The goal was to understand how lifestyle factors might affect…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: Universidad Rey Juan Carlos • Aim: Knowledge-focused
Last updated May 17, 2026 04:12 UTC
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Choline pills may harm arteries, small study hints
Knowledge-focused CompletedThis study looked at whether taking choline supplements for a short time changes how well blood vessels work in healthy adults. Twenty people took choline or a placebo for five days each, with a break in between. Researchers measured artery function and stiffness to see if cholin…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Choline pills may harm your arteries, new study suggests
Knowledge-focused CompletedThis study looked at whether taking choline supplements can temporarily harm blood vessel function in healthy adults. Researchers gave 29 participants either choline or a placebo and measured artery health using ultrasound. The goal was to understand how a gut-related chemical ca…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Stand up for your health: simple swap lowers blood sugar in High-Risk group
Knowledge-focused CompletedThis study looked at whether replacing sitting time with standing or walking can help control blood sugar in South Asian adults who are overweight or obese. Eighteen participants changed their daily routines to sit less and move more. The results showed that even small changes ca…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Bedfordshire • Aim: Knowledge-focused
Last updated May 12, 2026 13:44 UTC
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Exercise study reveals how workout intensity tames hunger hormones
Knowledge-focused CompletedThis study looked at how different exercise intensities change levels of ghrelin, a hormone that controls hunger, in 40 adults with obesity and prediabetes. Researchers measured ghrelin in the blood and checked appetite, insulin sensitivity, and blood vessel function. The goal wa…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated May 12, 2026 13:44 UTC
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OJ vs. soda: which is worse for your heart?
Knowledge-focused CompletedThis study looked at how drinking orange juice compared to a sugary drink affects risk factors for heart disease and type 2 diabetes. Fifty-six adults drank either orange juice or a sugar-sweetened beverage for four weeks. Researchers measured changes in cholesterol, blood sugar …
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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Salt sensitivity secrets revealed in small study
Knowledge-focused CompletedThis study looked at how salt in the diet affects blood pressure in Black adults. 19 participants ate both high-salt and low-salt diets to see how their bodies handled salt. The goal was to understand the link between salt and blood pressure, not to test a treatment.
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC
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Study probes hidden links between job stress and obesity in poor communities
Knowledge-focused CompletedThis research study looked at how stress, behavior, and social factors affect weight loss and heart health in people from disadvantaged backgrounds. Fifteen adults with overweight or obesity took part. The goal was to learn more about what helps or hinders weight management in th…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 04, 2026 16:21 UTC
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Teen diet and lifestyle may predict heart risk decades later
Knowledge-focused CompletedThis study followed 72 young adults who were part of a larger European study 10 years ago as teenagers. Researchers looked at their current heart disease risk using a special score and compared it to their diet and lifestyle habits from adolescence. The goal was to find which tee…
Matched conditions: CARDIOVASCULAR RISK FACTOR
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC