CARDIOVASCULAR RISK FACTOR

This study tested a culturally tailored lifestyle program called SAHELI for South Asian adults at risk for heart disease. The program focused on diet and physical activity changes. Researchers compared the program to standard health education materials in 550 participants. The go…

This completed early-phase trial tested whether switching HIV medications to doravirine (with emtricitabine and tenofovir alafenamide) could improve cholesterol and reduce early signs of artery hardening compared to staying on integrase inhibitors. Twenty-six adults with well-con…

This study tested a new weight loss program called Med-South, which adapts the Mediterranean diet for Southern tastes, against the popular WW (Weight Watchers) program. Over 360 adults with obesity participated for 2 years, with researchers tracking weight loss, blood markers, an…

This study tested a 1-year online program designed to help adults aged 40-70 who are at risk for heart disease become more physically active. Participants either received a fitness tracker plus online coaching and goal-setting sessions, or just a fitness tracker with standard act…

This study tested whether drinking a ketone supplement three times a day for two weeks could improve blood vessel health and thinking skills in adults aged 50-75. Eleven participants each tried the ketone drink and a placebo, with a two-week break in between. The goal was to see …

This study looked at whether a regular stretching routine could improve heart health in pregnant women with obesity. 224 women were assigned to either a stretching program or usual care (moderate exercise). The researchers measured blood pressure and other heart-related markers f…

This study looked at how sleep, body clocks, and daily habits affect nighttime blood pressure in Black adults. Researchers monitored 30 participants in a lab for a week to measure blood pressure changes. The goal is to find better ways to treat high blood pressure by targeting sl…

This study looked at how salt affects blood pressure in Black adults. Researchers wanted to see if changes in blood pressure from eating more or less salt were linked to signs seen on medical scans. 19 people took part, and the goal was to learn more, not to test a new treatment.

This study looked at whether taking short, regular walks during long periods of sitting can lower blood sugar and cholesterol after meals—key risk factors for Type 2 diabetes and heart disease. Researchers compared the effects in normal-weight and overweight/obese South Asian adu…

This study tested whether taking choline supplements for a short time affects blood vessel function in 20 healthy adults. Choline is a nutrient found in foods like eggs and meat, but when gut bacteria break it down, it produces a compound called TMAO, which has been linked to hea…

This completed study looked at 61 adults to see if physical fitness, body composition, and diet are linked to gum disease severity. Researchers reviewed dental records and lifestyle questionnaires from a previous study. No new treatments were tested; the goal was simply to unders…

This study looked at whether taking a choline supplement (1000 mg) the night before affects blood vessel function in 29 healthy adults. Participants took either choline or a placebo, then had their artery function measured. The goal was to see if choline, which raises a gut-relat…

This study tested whether replacing sitting with standing or walking during daily life could improve blood sugar levels in South Asian adults who are overweight or obese. Eighteen participants followed two regimens: one with more sitting and one with less sitting. The goal was to…

This study looked at 90 people with low or medium heart risk to see if tiny, non-blocking plaques in the heart arteries affect how blood clots and how blood vessels work. Participants had a special CT scan to find these small plaques, and their blood was tested for clotting activ…

This study looked at whether treating insomnia can reduce the risk of heart disease in people with PTSD. Researchers measured blood pressure, blood vessel health, and other heart risk factors in 140 adults aged 40-59. The goal was to see if improving sleep could also improve hear…

This study followed 72 young adults who were part of a larger European study 10 years ago as teenagers. Researchers looked at their current heart disease risk using a special score and compared it with their diet and lifestyle habits from adolescence. The goal is to find new risk…

This study looked at how a single high-salt meal affects blood pressure and blood vessel function in healthy adults aged 19-40. Researchers compared Black and white participants to see if there are racial differences in how the body handles salt. The goal is to understand why Bla…

This study looked at how stress, behavior, and social factors affect weight loss and heart health in people from disadvantaged backgrounds. 15 adults with overweight or obesity took part. Researchers measured weight, waist size, and heart health over time to understand what helps…

This study looked at how drinking orange juice compared to a sugar-sweetened beverage affects risk factors for heart disease and type 2 diabetes. Fifty-six adults drank either orange juice or a sugary drink for four weeks. Researchers measured changes in cholesterol, blood sugar,…

This study looked at how choline from eggs or supplements affects levels of TMAO, a compound linked to higher heart disease risk. Researchers gave 86 healthy adults either whole eggs, egg whites, choline supplements, or phosphatidylcholine capsules for 28 days. The goal was to se…

This study looked at how different exercise intensities affect ghrelin, a hormone that controls hunger, in 40 adults with obesity or prediabetes. Participants cycled on a stationary bike while researchers measured ghrelin levels, appetite, and blood vessel function. The goal was …