CARDIOVASCULAR DISEASES (CVD)

This study tests a new device called the VDyne System to replace the tricuspid valve in people with severe leakage that causes symptoms like shortness of breath and fatigue. About 730 adults who still have symptoms despite medication will be enrolled. The goal is to see if the de…

This study tests a new device called the BrioVAD, a mechanical heart pump for people with advanced heart failure that doesn't respond to standard treatments. About 60 adults with severe symptoms will receive the pump to help their heart pump blood. The main goal is to see how man…

This study tests whether taking a daily fiber supplement (WellBiome) for 6-8 weeks before heart surgery can improve recovery. 80 adults aged 50-80 with certain health markers will be randomly assigned to get the supplement or a placebo. Researchers will measure time in the ICU, c…

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect heart disease risk factors in 80 adults with prediabetes. Participants will be randomly assigned to consume one sweetener or water for two weeks. Researchers will measure ch…

This study will collect heart sound and ECG recordings from 1,000 adults undergoing routine echocardiograms. The goal is to see if artificial intelligence can accurately detect pulmonary hypertension and other heart conditions from these recordings. If successful, this could lead…

This study tests a new way to collect health data for heart disease prevention. Researchers want to see if 450 adults will voluntarily share information from their wearable devices (like smartwatches) and health apps. The goal is to make heart health research more inclusive by in…

This study looks at whether the supplement quercetin can help blood vessels work better in people with obesity. Researchers will measure how small blood vessels respond to certain substances. 40 participants aged 18-40 with a BMI over 30 will be involved. The goal is to understan…