CARDIOPULMONARY BYPASS

This study tested a special heart-protection plan given during cardiac surgery to see if it could reduce heart muscle damage compared to standard care. It involved 210 adults having aortic valve surgery at multiple French hospitals. Researchers measured a heart damage marker in b…

This study tested whether dexmedetomidine, a sedative that preserves breathing better than other drugs, can protect the heart during cardiac bypass surgery. Researchers measured heart damage in 224 adults undergoing heart surgery with a heart-lung machine. The goal was to see if …

This study tested a new way to decide when to give blood transfusions during heart surgery. Instead of using a fixed hemoglobin level, doctors used a measure of oxygen in the blood (SvO2) to guide transfusions. The goal was to see if this approach could safely reduce the number o…

This study tested whether giving a low dose of dexmedetomidine (a mild sedative) at night can prevent delirium—sudden confusion and disorientation—in older adults after heart surgery. Researchers enrolled 504 patients aged 60-89 who had heart surgery with a heart-lung machine. Th…

This study looked at 60 obese patients having heart surgery with a heart-lung machine. It compared two ways of giving the blood thinner heparin: one based on actual body weight and one based on ideal body weight. The goal was to see if using ideal body weight could prevent too mu…

This study tested whether using low tidal volume (gentle) ventilation during heart-lung bypass surgery could lower the risk of postoperative delirium (sudden confusion). 130 adults having planned heart surgery were randomly assigned to receive either gentle ventilation or no vent…

This study looked at two different solutions used to protect the heart during coronary artery bypass surgery. 40 adults having planned bypass surgery took part. Researchers checked blood samples, X-rays, ECGs, and recovery data from the first 48 hours after surgery to see which s…

This study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect changes in brain pressure during open-heart surgery when a heart-lung machine is used. Forty adults having elective heart surgery were enrolled. The goal wa…

This study looked at 68 adults having planned open-heart surgery to see if the type of oxygenator (artificial lung) used in the heart-lung machine affects how well platelets work. Platelets are blood cells that help stop bleeding. The researchers used a special test to measure pl…

This study looked at 38 adults who had heart surgery to understand the damage that happens to the heart muscle during the procedure. Researchers used heart MRI scans and blood tests (troponin levels) to measure and compare the amount of injury. The goal was to better understand t…

This study looked at 80 adults having heart valve or aortic surgery to find out how long Del Nido cardioplegia (a solution that temporarily stops the heart) keeps the heart muscle safe. Researchers took blood samples during and after surgery to measure when heart injury starts. T…

This study looked at 40 heart surgery patients to understand why blood pressure readings can differ between the body's center and arms during use of a heart-lung machine. Researchers measured pulse wave speed at the thigh, upper arm, and wrist to find a better way to detect these…