CARDIOPULMONARY BYPASS
Clinical trials for CARDIOPULMONARY BYPASS explained in plain language.
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New heart surgery strategy aims to protect Patients' hearts
Disease control CompletedThis study tested whether a combination of protective treatments during heart valve surgery could reduce heart muscle damage compared to standard care. Researchers enrolled 210 patients undergoing aortic valve surgery and measured heart injury markers for 72 hours after surgery. …
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Heart surgery study aims to cut unnecessary blood transfusions
Disease control CompletedThis study tested whether doctors could safely give fewer blood transfusions during heart surgery by using a special monitor that checks if the body's tissues are getting enough oxygen. Researchers compared two groups of 676 adult patients: one group received transfusions based o…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New dosing method aims to cut bleeding risk in obese heart surgery patients
Disease control CompletedThis study tested a new way to calculate the dose of the blood-thinner heparin for obese patients during heart surgery using a heart-lung machine. Researchers compared dosing based on a patient's ideal body weight versus their total weight to see if it prevented excessive blood t…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: PHASE4 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Sedative tested as heart protector in major surgery
Disease control CompletedThis study tested whether a sedative drug called dexmedetomidine could help protect the heart during and after major open-heart surgery. Researchers enrolled 224 patients undergoing this type of surgery to see if the drug reduced levels of a protein that signals heart muscle dama…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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MRI scans reveal hidden heart damage after surgery
Knowledge-focused CompletedThis study aimed to better understand the heart muscle damage that can occur during open-heart surgery using a heart-lung machine. Researchers used detailed heart MRI scans and frequent blood tests to measure this damage in 38 patients who had aortic valve surgery. The goal was t…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Apr 02, 2026 07:12 UTC
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Doctors test eye scan as window to the brain during risky heart operations
Knowledge-focused CompletedThis study tested if a simple, non-invasive eye ultrasound could be used to monitor brain pressure in patients undergoing open-heart surgery. Researchers measured the width of the optic nerve sheath in the eye at different times during the procedure to see if it reliably indicate…
Matched conditions: CARDIOPULMONARY BYPASS
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Heart surgery study tests which protection method works better
Knowledge-focused CompletedThis study compared two different solutions used to protect the heart during coronary artery bypass surgery. Researchers followed 40 adult patients having bypass surgery to see which solution better protected heart muscle. They measured heart injury markers in blood samples and t…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: PHASE4 • Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Doctors probe hidden blood pressure gaps in heart surgery
Knowledge-focused CompletedThis study aimed to understand why blood pressure readings can differ between the body's core and limbs during heart-lung bypass surgery. Researchers measured pulse waves in 40 patients undergoing scheduled heart surgery to see if this difference could be reliably detected. The g…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC