Lighter breathing on Heart-Lung machine may cut Post-Surgery delirium

NCT ID NCT06752421

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether using low tidal volume (gentle) ventilation during heart-lung bypass surgery can lower the risk of postoperative delirium—a state of confusion that can slow recovery. Researchers compared 130 patients who received either low tidal volume ventilation or no ventilation during bypass. The main goal was to see if the gentle breathing approach reduced delirium rates, ICU stay, and 30-day complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low tidal volume ventilation (a breathing machine setting during surgery)

What this could lead to

If it works, this could point toward a simple way to lower confusion and improve recovery after heart surgery.

What could go wrong

This is a small, single-center trial. The results may not apply to all patients or hospitals, and the effect on delirium may be small or absent.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction coronary artery disorder Emergence Delirium Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Konya City Hospital

    Konya, Karatay, 42030, Turkey (Türkiye)