CARDIOMYOPATHY

This early-stage study is testing whether stem cells from donor bone marrow can help improve heart function in cancer survivors who developed heart damage from certain chemotherapy drugs. Researchers will compare two different methods of delivering the stem cells (through an IV o…

This study is testing whether an 8-week exercise program done at home or in the community can improve fitness and quality of life for adults with reduced heart or lung function. Researchers will compare 200 participants who do the exercise program to those who do not. The program…

This study aims to find out which of two commonly used heart failure medications works better for patients who also have an implanted defibrillator. It will follow 2,000 participants for up to 3 years to see which drug leads to fewer defibrillator shocks, fewer hospital visits, a…

This study is testing a new paddle-shaped catheter designed to create detailed maps of irregular heartbeats. The device will be used in 60 patients with conditions like atrial fibrillation and ventricular tachycardia who are already scheduled for a heart procedure. Researchers wa…

This study aims to identify blood markers that can predict which breast cancer patients might develop heart problems from chemotherapy. Researchers will collect blood samples from 200 patients before and after treatment to look for genetic clues. The goal is to help doctors inter…

This study aims to understand how heart disease develops in people with Friedreich Ataxia, a rare genetic disorder. Researchers will follow 65 participants over time to track changes in heart structure and function. The goal is to gather detailed information that could help desig…

This study aims to learn more about rare and poorly understood diseases that affect the heart and blood vessels. Researchers will enroll up to 5,000 people, including patients, their relatives, and healthy volunteers, to collect medical data, images, and samples. The goal is to i…

This study aims to better understand how a protein buildup called amyloid damages the heart in people with light chain amyloidosis. Researchers will use advanced PET and MRI scans to visualize the amyloid in the heart and measure how it affects heart function and metabolism. The …

This early-stage study aims to understand how a new drug for a heart muscle disease (cardiomyopathy) is absorbed by the body. It will test two different pill versions and see if taking the pill with food changes how it works. The study involves 38 healthy adults and will closely …

This study aims to find the specific genes that cause inherited heart and muscle diseases like cardiomyopathy and muscular dystrophy. Researchers will analyze DNA from up to 2,000 patients and their family members who have these conditions. The goal is to better understand the ge…