CARDIOMYOPATHY

This study compares two common heart failure medications, carvedilol and metoprolol succinate, in 2,000 adults who have an implantable defibrillator (ICD). Participants currently taking metoprolol will be randomly assigned to either stay on it or switch to carvedilol. The goal is…

This study tests whether stem cells from a donor can help control heart failure in people whose hearts were weakened by a type of chemotherapy called anthracyclines. About 72 adults with low heart function will receive either standard care alone or standard care plus stem cells g…

This study tests whether artificial intelligence (AI) can help doctors interpret heart ultrasound (echo) images more accurately and quickly. Researchers at Mayo Clinic will deploy AI tools to assist in diagnosing conditions like cardiomyopathy, coronary artery disease, and cardia…

This study looks at whether exercising in your community or at home can improve how well your heart and lungs work. Researchers will compare people who exercise regularly with those who don't. The goal is to find a safe and effective way for people with conditions like heart dise…

This study is looking at a protein called TRPC6 in the blood to see if it can predict which breast cancer patients will develop heart problems from chemotherapy. Researchers will collect blood samples from 200 patients to study genetic changes linked to heart damage. The goal is …

This study involves 171 adults with light chain amyloidosis, a condition where abnormal proteins build up in the heart. Researchers will use special PET and MRI scans to track these deposits and measure heart function over 6 to 12 months. The goal is to better understand what cau…

This study is testing a new paddle-shaped catheter designed to map abnormal heart rhythms (arrhythmias) in the upper and lower chambers of the heart. About 60 people with conditions like atrial fibrillation or ventricular tachycardia will take part. The main goal is to check if t…

This study aims to find the genes and mutations that cause inherited heart conditions like cardiomyopathy and arrhythmia, as well as muscular dystrophy. Researchers will collect DNA samples from patients and their families, focusing on those with multiple affected relatives. The …

This study watches how heart disease develops and changes over time in people with Friedreich ataxia, a rare genetic condition. Researchers will measure heart muscle thickness and mass using imaging. The goal is to learn more about the disease to help design future treatments. Ab…

This study aims to better understand heart and blood vessel diseases by observing people who have them or are at risk. Researchers will collect medical information, images, and samples from up to 5,000 participants, including healthy volunteers and family members. The goal is to …

This study checks if two different tablet forms of the drug HRS-1893 are processed the same way in the body. It involves 36 healthy adults aged 18 to 55. The main goal is to measure drug levels in the blood, not to treat any condition.

This study aims to understand how different genetic changes in the DMD gene are linked to heart problems in boys and young men (ages 2-24) with Duchenne or Becker muscular dystrophy. Researchers will use heart tests and blood samples to find early signs of heart issues. The study…