BRCA2 GENE MUTATION
Clinical trials for BRCA2 GENE MUTATION explained in plain language.
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New drug shows promise in shrinking ovarian tumors before surgery
Disease control OngoingThis early-phase trial tests the drug olaparib in 15 people with newly diagnosed BRCA-mutant ovarian, fallopian tube, or peritoneal cancer. Participants take olaparib for two cycles before their planned surgery to see if it can shrink tumors safely. The goal is to find out if thi…
Matched conditions: BRCA2 GENE MUTATION
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 29, 2026 08:03 UTC
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Immunotherapy shows promise for Hard-to-Treat cancers with specific gene mutations
Disease control OngoingThis study tested the drug pembrolizumab (a type of immunotherapy) in 21 adults with advanced solid tumors that have specific gene mutations (BRCA1, BRCA2, POLE, or POLD1). The goal was to see if the drug could shrink or control the cancer. Participants received pembrolizumab int…
Matched conditions: BRCA2 GENE MUTATION
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Apr 29, 2026 08:03 UTC