New drug combo targets tough prostate cancer in understudied groups

NCT ID NCT06392841

Terminated Disease control Sponsor: Qian Qin Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 25 times

Summary

This study tested a combination of two drugs, niraparib and abiraterone (plus prednisone), for Hispanic/Latino and Black patients with a specific type of advanced prostate cancer that has spread and has certain gene changes. The goal was to see if the treatment could lower PSA levels significantly. However, the study was withdrawn before enrolling any participants, so no results are available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

Explore the condition pages connected to this study.

BRCA1 GENE MUTATION BRCA1 GENE MUTATION BRCA2 GENE MUTATION BRCA2 GENE MUTATION BRIP1 GENE MUTATION CHEK2 GENE MUTATION DELETERIOUS HRR GENE MUTATION FANCA GENE MUTATION METASTATIC HORMONE-SENSITIVE PROSTATE CANCER (MHSPC) PALB2 GENE MUTATION RAD51B GENE MUTATION RAD51B GENE MUTATION RAD51B GENE MUTATION RAD54L GENE MUTATION RAD54L GENE MUTATION