New hope for Hard-to-Treat cancers: drug targets genetic weakness
NCT ID NCT02286687
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 26 times
Summary
This study tests a drug called talazoparib in people with advanced cancers that have not responded to standard treatments. The drug works by blocking an enzyme that helps cancer cells survive, especially in tumors with changes in BRCA or related genes. The goal is to see if the drug can shrink tumors or slow their growth. About 150 adults with various cancer types (excluding breast and ovarian) are taking part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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