ATM GENE MUTATION
Clinical trials for ATM GENE MUTATION explained in plain language.
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New drug cocktail targets cancers with faulty DNA repair
Disease control Recruiting nowThis early-stage trial is testing whether combining two drugs—niraparib and irinotecan—can safely treat advanced solid tumors that have mutations in DNA repair genes like BRCA. The study will enroll 24 adults with various cancers, including breast, ovarian, pancreatic, and others…
Matched conditions: ATM GENE MUTATION
Phase: PHASE1 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New drug combo targets tough cancers in early trial
Disease control Recruiting nowThis early-phase study tests a combination of two oral drugs, olaparib and ASTX727, in adults with advanced solid tumors that have mutations in genes like BRCA1, BRCA2, PALB2, ATM, or CHEK2. The main goals are to find the safest dose and to check for side effects. About 18 partic…
Matched conditions: ATM GENE MUTATION
Phase: PHASE1 • Sponsor: Varun Monga, MBBS • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New scan may improve cancer detection for men with inherited risk
Diagnosis Recruiting nowThis study compares a new PET-CT scan (FCH-PET-CT) to standard imaging (bone scan and MRI/CT) to see which better finds cancer that has spread outside the pelvis in men with prostate cancer and specific DNA repair gene mutations. About 50 men with these mutations will be enrolled…
Matched conditions: ATM GENE MUTATION
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
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Can digital tools make cancer genetic counseling more effective?
Knowledge-focused Recruiting nowThis study looks at two new approaches to cancer genetic counseling. The first helps doctors reach out to family members who may have inherited a cancer-related gene change, making it easier for them to get tested. The second uses an online portal to keep patients and their docto…
Matched conditions: ATM GENE MUTATION
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC