BRCA2 GENE MUTATION
Clinical trials for BRCA2 GENE MUTATION explained in plain language.
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Targeted pill trial offers hope for tough cancers with genetic flaw
Disease control OngoingThis study is testing an oral medication called talazoparib for people with advanced cancers that have spread, returned, or stopped responding to standard treatments. It is specifically for patients whose cancers have certain genetic changes in the BRCA pathway (like BRCA1, BRCA2…
Matched conditions: BRCA2 GENE MUTATION
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope: testing targeted drug before surgery for aggressive ovarian cancer
Disease control OngoingThis early study is testing whether a drug called olaparib can help shrink tumors before surgery in people newly diagnosed with advanced ovarian cancer that has a BRCA gene mutation. The trial involves about 15 participants who will take olaparib pills for up to two months before…
Matched conditions: BRCA2 GENE MUTATION
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Targeted prostate cancer trial for hispanic and black men withdrawn before start
Disease control TerminatedThis study aimed to test a combination of two drugs, niraparib and abiraterone, plus a steroid, in men with newly diagnosed, advanced prostate cancer that had spread and had specific genetic changes. It specifically sought Hispanic/Latino and non-Hispanic Black participants to se…
Matched conditions: BRCA2 GENE MUTATION
Phase: PHASE2 • Sponsor: Qian Qin • Aim: Disease control
Last updated Mar 09, 2026 14:23 UTC
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Can text messages and phone calls help prevent cancer?
Prevention OngoingThis study is testing different ways to help people at high risk for cancer or cancer survivors become more active and eat healthier foods. Researchers are comparing methods like weekly phone calls, emails, daily text messages, and online forums to see which combinations work bes…
Matched conditions: BRCA2 GENE MUTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Apr 01, 2026 14:43 UTC
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Researchers test best way to deliver scary genetic news
Knowledge-focused TerminatedThis study aims to find the best way to help women understand their genetic cancer risk with less stress. It compares watching an online educational video alone to combining it with phone counseling sessions. The goal is to see which method helps participants feel less distressed…
Matched conditions: BRCA2 GENE MUTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC