BRAIN METASTASES, ADULT

This study tests a treatment for people with advanced lung cancer that has spread to the brain. It combines two immunotherapy drugs (nivolumab and ipilimumab) with a short course of chemotherapy. The goal is to see if this approach can control the brain tumors for at least 6 mont…

This early-phase study tests whether a special PET scan (68Ga-PSMA-11) can detect tumor activity in people with high-grade glioma or brain metastases. Eleven adults with suspected or confirmed tumors will receive the scan before a planned biopsy or surgery. The goal is to measure…

This study looks at two ways to give radiation to people with cancer that has spread to the brain. All participants are also receiving immunotherapy. The standard approach gives a single high dose of radiation, while the experimental approach gives a lower dose over a few days. T…

This study reviews medical records from 700 adults with colorectal cancer that spread to the brain. Researchers will analyze which local treatments (like surgery or radiation) were used and how long patients lived or stayed free of brain tumor growth. No new treatments are given;…

This pilot study explores whether people with brain metastases can stick to a ketogenic (high-fat, low-carb) diet for 16 weeks while undergoing radiosurgery. Researchers will compare this to a standard healthy diet, tracking diet adherence, blood markers, and quality of life. The…