BACTERIAL INFECTIONS

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This study tested a new, portable blood culture system called BactInsight in hospitals in Benin and Burkina Faso. The system uses a battery-powered device to detect bacteria in blood samples faster than current manual methods. Researchers compared it to standard lab tests in over…

This study tested a blood test that measures three proteins (ICAM1, CFHR5, and GRN) to help doctors quickly tell whether a fever is caused by bacteria or a virus. Researchers studied 394 adults with high fever and short illness duration. The goal is to improve diagnosis and reduc…

This study tested whether giving mothers a single 2-gram dose of the antibiotic azithromycin during labour could reduce the risk of skin and soft tissue infections in their babies during the first three months of life. Over 2,000 pregnant women in Fiji took part, receiving either…

This study tested whether a probiotic called Bifidobacterium breve PRL2020 could reduce stomach issues like diarrhea in 121 children aged 3-12 who were taking amoxicillin antibiotics. The children took the probiotic alongside their antibiotic treatment. The goal was to see if it …

This study looks at why some medications, like the antifungal voriconazole, can cause extreme sensitivity to sunlight, leading to severe sunburn-like reactions. Researchers will measure gene activity in skin samples from 62 participants, including healthy volunteers and patients …

This early-phase study tested a single dose of the antibiotic omadacycline (Nuzyra) in 23 children aged 8 to 17 who were hospitalized with bacterial infections. Researchers measured how the drug moved through the body and checked for side effects. The goal was to gather safety an…

This study tested a new imaging technique using a radioactive tracer called 11C-trimethoprim to see how it spreads in the bodies of 16 adults with suspected bacterial infections. Participants had PET/CT scans to track the tracer over time. The goal was to learn how the tracer beh…

This early-stage trial tested the safety and drug interactions of an experimental oral antibiotic combination (QPX7831 plus ceftibuten) in 53 healthy adults. The goal was to see how the body processes the drugs and whether they cause side effects. Results will help decide safe do…

This completed Phase 1 study tested a combination of two antibiotics, cefiderocol and xeruborbactam, in 60 healthy adults. The goal was to see how the drugs interact in the body and whether they are safe. Participants received either the drug combo or a placebo, and researchers m…