BACTERIAL INFECTIONS

This early-stage study tested a new oral antibiotic combination in healthy adults to see if it is safe and how the two drugs interact in the body. The study involved 53 healthy participants who received the drugs alone and together for up to 10 days. The main goal was to measure …

This small, early-stage study tested a new radioactive tracer called 11C-PABA for PET scans. The goal was to see if this tracer could help doctors better locate infections in the body and tell them apart from other problems like inflammation or cancer. Researchers scanned 13 adul…

This study tested a new blood test designed to quickly tell if a person's fever is caused by a bacterial infection or a viral one. Researchers used artificial intelligence to find specific proteins in the blood that signal the type of infection. The goal is to help doctors prescr…

This study tested a new, simple, and portable system called BactInsight for diagnosing bloodstream infections in hospitals in Benin and Burkina Faso. The goal was to see if this easy-to-use system could work as well as standard lab equipment in places where advanced labs are scar…

This large study tested whether giving a single dose of the antibiotic azithromycin to mothers during labor could prevent skin and other infections in their babies during the first year of life. Over 2,100 mother-baby pairs in Fiji participated, with half receiving the antibiotic…

This study tested whether a specific probiotic (Bifidobacterium breve PRL2020) could help reduce stomach problems like diarrhea, cramps, and bloating in children aged 3-12 who were taking common antibiotics (amoxicillin) for infections. Researchers wanted to see if this 'friendly…

This early-stage study tested how two antibiotics work together in healthy adults. Researchers gave 60 healthy volunteers either the drug combination or a placebo to check for safety issues and measure how the drugs move through the body. The goal was to gather basic safety infor…

This early-stage study tested how children's bodies process a single dose of the antibiotic omadacycline. It involved 23 hospitalized children and teenagers who already had a suspected or confirmed bacterial infection. Researchers measured drug levels in the blood and checked for…

This study aimed to understand why some people taking certain medications, like the antifungal drug voriconazole, develop a severe sunburn-like reaction to light. Researchers tested 62 participants, including healthy volunteers and patients on the medication, by exposing small pa…

This early-phase study aimed to understand how a radioactive tracer based on an antibiotic moves through the body in people with suspected bacterial infections. Researchers used PET/CT scans to track the tracer in up to 30 adult participants. The goal was to gather basic knowledg…