AUTOIMMUNE DISEASE

This study is for people who have both an autoimmune disorder (like rheumatoid arthritis, lupus, or multiple sclerosis) and advanced cancer that has spread or cannot be removed. It tests a drug called nivolumab, which helps the immune system fight cancer, given alone or with othe…

This study tests if the antiviral drug remdesivir can safely treat RSV (a common respiratory virus) in 60 adults whose immune systems are weakened by cancer treatments or autoimmune therapies. Participants must have a confirmed RSV infection with symptoms. The main goal is to see…

This early-stage study tests a single injection of GenSci136 in 48 healthy adults to see if it is safe and how the body processes it. The drug is being developed for autoimmune diseases, where the immune system attacks the body. Participants are randomly assigned to receive eithe…

This study is testing whether combining two immune-suppressing drugs, rituximab and cyclosporine, can safely and effectively treat membranous nephropathy, a kidney disease where the immune system attacks the kidneys, causing protein to leak into urine. About 30 adults with persis…

This study collects DNA samples from 1200 adults receiving routine care at the University of Chicago. Researchers test for genetic differences that could affect how patients respond to certain medications, including risk of side effects. The results are shared with their doctors,…

This study is testing a new educational tool designed for people with melanoma who also have an autoimmune disease (like rheumatoid arthritis or Crohn's disease) and may receive immune checkpoint inhibitor drugs. Researchers want to see if the tool is easy to use and helpful for …

This study follows 900 people with bronchiectasis (damaged and infected airways) to learn why they get repeated lung infections. Researchers will collect blood, spit, and genetic samples from patients and their family members. The goal is to find inherited or immune system proble…