ATYPICAL ENDOMETRIAL HYPERPLASIA
Clinical trials for ATYPICAL ENDOMETRIAL HYPERPLASIA explained in plain language.
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Hormone showdown: which progestin best tames uterine cancer before surgery?
Disease control Recruiting nowThis study compares two hormone drugs (megestrol acetate and micronized progesterone) in 140 women with endometrial cancer or precancer. Participants take one of the drugs for a short time before their scheduled surgery. Researchers will measure how well each drug slows cancer ce…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Phase: PHASE2 • Sponsor: New Mexico Cancer Research Alliance • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Can weight management plus hormones reverse precancerous uterine changes and preserve fertility?
Disease control Recruiting nowThis study is for overweight or obese women aged 18–45 with atypical endometrial hyperplasia, a precancerous condition of the uterine lining. Participants will receive either a levonorgestrel-releasing IUD (Mirena) or megestrol acetate pills, combined with a weight management pro…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Phase: PHASE2, PHASE3 • Sponsor: Xiaojun Chen • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New collagen shot may help young women beat uterine cancer without hysterectomy
Disease control Recruiting nowThis study tests whether injecting a lab-made collagen into the uterus, along with daily hormone pills, can help shrink early-stage endometrial cancer or precancerous growths. The goal is to preserve fertility in women aged 45 or younger. Thirty participants will either receive t…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Phase: PHASE2 • Sponsor: Wang Jianliu • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Weight loss program may help women avoid hysterectomy and preserve fertility
Disease control Recruiting nowThis study tests whether adding a behavioral weight loss program to standard hormone therapy helps premenopausal women with obesity and early endometrial cancer or precancer keep their uterus and fertility. About 96 women will receive either the weight loss program plus hormone t…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Swab test could spot hidden uterine cancer early
Diagnosis Recruiting nowThis study is collecting vaginal fluid samples from 4,200 people to develop a new test for endometrial cancer. Participants include those with abnormal uterine bleeding or a recent endometrial cancer diagnosis. The goal is to find biomarkers that could lead to a simple, non-invas…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Sponsor: Exact Sciences Corporation • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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Could a vaginal swab detect multiple cancers? mayo clinic launches major study
Diagnosis Recruiting nowThis study aims to develop a screening test that uses a vaginal swab and blood sample to find DNA markers for endometrial, ovarian, and cervical cancers. Researchers at Mayo Clinic will enroll over 3,000 women to see if the test can accurately detect these cancers at an early sta…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 12:08 UTC