ASCVD
Clinical trials for ASCVD explained in plain language.
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Phone coach after heart attack may slash cholesterol and save lives
Disease control Recruiting nowThis trial tests whether a 'care champion' — a person who calls patients after they leave the hospital following a heart attack or stent procedure — can help them get their LDL cholesterol to a healthy level. Participants also receive education for their doctors. The study compar…
Matched conditions: ASCVD
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Can a drug calm heart inflammation in people with TET2 mutations?
Disease control Recruiting nowThis study tests whether canakinumab, an anti-inflammatory drug, can reduce blood vessel inflammation in people with coronary artery disease. Some participants have a genetic change called TET2 clonal hematopoiesis, which may increase inflammation. 120 adults will receive either …
Matched conditions: ASCVD
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New pill aims to unclog arteries in heart disease patients
Disease control Recruiting nowThis study tests a new daily pill called ABP-745 in 200 adults with atherosclerosis (hardening of the arteries from plaque buildup). Participants will take either a low, medium, or high dose of ABP-745 or a placebo for 52 weeks. The main goal is to see if the drug can reduce the …
Matched conditions: ASCVD
Phase: PHASE2 • Sponsor: Atom Therapeutics Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Massive diabetes trial aims to find which drug saves hearts and kidneys best
Disease control Recruiting nowThis study compares two common diabetes drug classes—SGLT2 inhibitors and GLP-1 receptor agonists—to see which better prevents heart attacks, strokes, kidney failure, and death in 6,000 people with type 2 diabetes and heart disease or high risk. Participants are randomly assigned…
Matched conditions: ASCVD
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Could a blood pressure cuff cut heart attacks and strokes?
Disease control Recruiting nowThis study tests whether a simple, non-invasive procedure called remote ischemic conditioning (RIC) can protect major organs in people with very high-risk atherosclerotic cardiovascular disease (ASCVD). RIC involves inflating a blood pressure cuff on the arms for short periods to…
Matched conditions: ASCVD
Sponsor: General Hospital of Shenyang Military Region • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Hidden heart risks in testicular cancer survivors: a closer look at chemotherapy's long shadow
Knowledge-focused Recruiting nowThis study investigates whether testicular cancer survivors who received cisplatin-based chemotherapy and bone marrow transplant have hidden heart disease that standard checkups might miss. Researchers will use advanced blood tests and CT scans to measure cholesterol, plaque in t…
Matched conditions: ASCVD
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC