Can a single drug calm inflamed arteries in people with a common gene change?
NCT ID NCT06691217
First seen Oct 31, 2025 · Last updated May 11, 2026 · Updated 27 times
Summary
This study tests whether the drug canakinumab can lower inflammation in the blood vessels of people who have had a heart attack or stent, and who may also have a specific genetic change called TET2. About 120 adults will receive either canakinumab or a placebo. The main goal is to see if the drug reduces signs of inflammation around the heart arteries, which could help manage heart disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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