ASCVD
Clinical trials for ASCVD explained in plain language.
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Can a drug calm heart inflammation in people with TET2 mutations?
Disease control Recruiting nowThis study tests whether canakinumab, an anti-inflammatory drug, can reduce blood vessel inflammation in people with coronary artery disease. Some participants have a genetic change called TET2 clonal hematopoiesis, which may increase inflammation. 120 adults will receive either …
Matched conditions: ASCVD
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New pill aims to unclog arteries in heart disease patients
Disease control Recruiting nowThis study tests a new daily pill called ABP-745 in 200 adults with atherosclerosis (hardening of the arteries from plaque buildup). Participants will take either a low, medium, or high dose of ABP-745 or a placebo for 52 weeks. The main goal is to see if the drug can reduce the …
Matched conditions: ASCVD
Phase: PHASE2 • Sponsor: Atom Therapeutics Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Massive diabetes trial aims to find which drug saves hearts and kidneys best
Disease control Recruiting nowThis study compares two common diabetes drug classes—SGLT2 inhibitors and GLP-1 receptor agonists—to see which better prevents heart attacks, strokes, kidney failure, and death in 6,000 people with type 2 diabetes and heart disease or high risk. Participants are randomly assigned…
Matched conditions: ASCVD
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Could a blood pressure cuff cut heart attacks and strokes?
Disease control Recruiting nowThis study tests whether a simple, non-invasive procedure called remote ischemic conditioning (RIC) can protect major organs in people with very high-risk atherosclerotic cardiovascular disease (ASCVD). RIC involves inflating a blood pressure cuff on the arms for short periods to…
Matched conditions: ASCVD
Sponsor: General Hospital of Shenyang Military Region • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC