New drug aims to melt artery plaque in heart patients

NCT ID NCT07303777

First seen Jan 04, 2026 · Last updated May 08, 2026 · Updated 19 times

Summary

This study tests an experimental drug called ABP-745 in 200 adults with atherosclerosis (hardening of the arteries due to plaque buildup). The goal is to see if it can reduce plaque in the arteries better than a placebo. Participants will receive the drug or placebo for 52 weeks, and doctors will measure changes in plaque volume using imaging.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Friendship Hospital, Capital Medical University

    NOT_YET_RECRUITING

    Beijing, China

    Contact

  • Cardiovascular Institute of San Diego INC

    NOT_YET_RECRUITING

    San Diego, California, 91911, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cardiovascular Research Foundation of Southern California

    NOT_YET_RECRUITING

    Beverly Hills, California, 90210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cognivus

    NOT_YET_RECRUITING

    Wahroonga, Australia

    Contact

  • Core Research Group Pty Ltd

    NOT_YET_RECRUITING

    Brisbane, Australia

    Contact

  • Dalian Second Hospital

    NOT_YET_RECRUITING

    Dalian, China

    Contact

  • Guangdong Province Hospital

    NOT_YET_RECRUITING

    Guangzhou, China

    Contact

  • Huashan Hospital Fudan University

    NOT_YET_RECRUITING

    Shanghai, China

    Contact

  • Jiangsu Province Hospital

    NOT_YET_RECRUITING

    Nanjing, China

    Contact

  • Jinan Central Hospital

    NOT_YET_RECRUITING

    Jinan, China

    Contact

  • Nanjing Drum Tower Hospital

    NOT_YET_RECRUITING

    Nanjing, China

    Contact

  • NovaTrails

    NOT_YET_RECRUITING

    Newcastle, New South Wales, 2290, Australia

    Contact

    Contact Email: •••••@•••••

  • Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, China

    Contact

  • Peking University First Hospital

    NOT_YET_RECRUITING

    Beijing, China

    Contact

  • Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    NOT_YET_RECRUITING

    Shanghai, China

    Contact

  • Renmin Hospital of Wuhan University

    NOT_YET_RECRUITING

    Wuhan, China

    Contact

  • Shaanxi Provincial People's Hospital

    NOT_YET_RECRUITING

    Xi'an, China

    Contact

  • Shanghai General Hospital

    NOT_YET_RECRUITING

    Shanghai, China

    Contact

  • Sir Run Run Shaw Hospital of Zhejiang University School of Medicine

    NOT_YET_RECRUITING

    Hangzhou, China

    Contact

  • The Affiliated Hospital of Xuzhou Medical College

    NOT_YET_RECRUITING

    Xuzhou, China

    Contact

  • The First Affiliated Hospital of Soochow University

    NOT_YET_RECRUITING

    Suzhou, China

    Contact

  • The First Affiliated Hospital of Xian Jiaotong University

    NOT_YET_RECRUITING

    Xi'an, China

    Contact

  • The First Affiliated Hospital of Zhejiang University school of medicine

    NOT_YET_RECRUITING

    Hangzhou, China

    Contact

  • The Lundquist Institute

    NOT_YET_RECRUITING

    Torrance, California, 90502, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Second Affiliated Hospital of Xi'an Jiaotong University

    NOT_YET_RECRUITING

    Xi'an, China

    Contact

  • The Zhongshan Hospital Affiliated to Fudan University

    RECRUITING

    Shanghai, China

    Contact

  • Tianjin General Hospital

    NOT_YET_RECRUITING

    Tianjin, China

    Contact

  • UniSC Clinical Trials (Brisbane)

    NOT_YET_RECRUITING

    Brisbane, Australia

    Contact Email: •••••@•••••

    Contact

  • University of the Sunshine Coast Clinical Trials Unit - Morayfield

    NOT_YET_RECRUITING

    Morayfield, Queensland, 4506, Australia

    Contact

    Contact

  • Washington University School of Medicine, St.louis

    NOT_YET_RECRUITING

    St Louis, Missouri, 63130, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Wuxi People's Hospital

    NOT_YET_RECRUITING

    Wuxi, China

    Contact

  • Xuanwu Hospital Capital Medical University

    NOT_YET_RECRUITING

    Beijing, China

    Contact

  • Zhejiang Provincial People's Hospital

    NOT_YET_RECRUITING

    Hangzhou, China

    Contact

Conditions

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