ASCVD
Clinical trials for ASCVD explained in plain language.
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Computer alerts could boost cholesterol treatment in heart patients
Disease control OngoingThis study tests whether electronic alerts in medical records help doctors prescribe stronger cholesterol-lowering medications for heart disease patients with high LDL levels. About 400 adults with heart or blood vessel disease and LDL over 80 mg/dL, already on a statin, are rand…
Matched conditions: ASCVD
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 17, 2026 10:10 UTC
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Heart drug combo may cut diabetes risk in prediabetic patients
Disease control ENROLLING_BY_INVITATIONThis study tests whether a combination of a low-dose statin plus ezetimibe is better than a high-dose statin alone at preventing new diabetes in people with prediabetes and heart disease. About 4,000 adults aged 18-75 with prediabetes and a history of heart or artery disease will…
Matched conditions: ASCVD
Phase: PHASE4 • Sponsor: Seung-Whan Lee, M.D., Ph.D. • Aim: Disease control
Last updated May 17, 2026 10:04 UTC
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New study aims to help heart patients hit cholesterol targets
Disease control ENROLLING_BY_INVITATIONThis study looks at different methods to help people with high cholesterol and heart disease get their LDL ("bad") cholesterol to recommended levels. About 300 adults with or at high risk for artery disease will take part. Researchers will compare approaches to improve use of cho…
Matched conditions: ASCVD
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 17, 2026 10:04 UTC
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Massive study pits diabetes drugs against each other to protect hearts
Knowledge-focused OngoingThis study looks at medical records from 60,000 people with type 2 diabetes and obesity to compare three drugs (dulaglutide, semaglutide, tirzepatide) against an older drug (sitagliptin) for preventing heart attacks, strokes, and death. The goal is to see which drug works best in…
Matched conditions: ASCVD
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC