Can a gentler cholesterol combo prevent diabetes in heart patients?

NCT ID NCT05579626

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at 4,000 adults with prediabetes and heart disease to see if a low-intensity statin combined with ezetimibe is better than a high-intensity statin alone at preventing new diabetes. Participants will be followed to track diabetes development and heart health. The goal is to find a safer way to manage cholesterol without raising diabetes risk.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, South Korea

  • Bycheon Sejong Hospital

    Bucheon-si, South Korea

  • Catholic University of Korea, Seoul ST. Mary's Hospital.

    Seoul, South Korea

  • Chonnam National University Hospital

    Gwangju, South Korea

  • Chungbuk National University Hospital

    Cheonju, South Korea

  • Chungnam National University Hospital

    Jungnam, South Korea

  • Chungnam National University Sejong Hospital

    Daejeon, South Korea

  • Daegu Catholic University Medical Center

    Daegu, South Korea

  • Dong-A Medical Center

    Pusan, South Korea

  • Ewha womans university seoul hospital

    Seoul, South Korea

  • Gachon University Gil Medical Center

    Incheon, South Korea

  • Gangneung Asan Hospital

    Gangneung, South Korea

  • Gangwon National University Hospital

    Chuncheon, South Korea

  • Gyeongsang National University Changwon Hospital

    Changwon, South Korea

  • Gyeongsang National University Hospital

    Jinju, South Korea

  • Hallym University Dongtan Sacred Heart Hospital

    Hwaseong-si, South Korea

  • Inje University Busan Paik Hospital

    Pusan, South Korea

  • Inje University Haeundae Paik Hospital

    Haeundae, South Korea

  • Jeju National University Hospital

    Jeju City, South Korea

  • Kangdong Sacred Heart Hospital

    Seoul, South Korea

  • Keimyung University Dongsan Medical Center

    Daegu, South Korea

  • Konyang University Hospital

    Daejeon, South Korea

  • Korea University Anam Hospital

    Seoul, South Korea

  • Kosin University Gospel Hospital

    Pusan, South Korea

  • Pusan National University Yangsan Hospital

    Pusan, South Korea

  • The Catholic Univ. of Korea Eunpyeong St. Mary's hospital

    Seoul, South Korea

  • The Catholic University of Korea, St. Vincent's Hospital

    Suwon, South Korea

  • Ulsan university hospital

    Ulsan, South Korea

  • VHS Medical Center

    Seoul, South Korea

  • Yungnam universury Hospital

    Daegu, South Korea

  • the Catholic University of Korea, Daejeon St. Mary'S Hospital

    Daejeon, South Korea

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