AORTIC ANEURYSM

This study compares a new guidance system called LumiGuide to standard X-ray guidance during a complex type of aortic aneurysm repair. The goal is to see if LumiGuide reduces the amount of radiation patients are exposed to during the procedure. About 182 adults having this surger…

This study tests a new device called the NEXUS aortic arch stent graft system in 110 adults with serious conditions like aortic dissection or aneurysm affecting the aortic arch. The goal is to see if it is safe and effective at repairing the damaged area without major complicatio…

This study looks at a stent that doctors modify themselves to treat large aneurysms in the chest and belly area. The goal is to see if this custom approach is safer and works better than traditional open surgery. About 80 people aged 50 and older with aneurysms that need repair w…

This study is testing a new device called Rapidlink that helps surgeons repair or replace blood vessels branching off the main artery (aorta) during open heart surgery. About 150 adults who need this type of surgery will take part. The goal is to see if the device is safe and wor…

This study explores whether kinocardiography (KCG), a portable device that measures chest vibrations from heartbeats, can diagnose aortic valve disease and thoracic aortic aneurysm. Researchers will compare KCG readings with standard imaging in 180 adults, including those with an…

This study is creating a large collection of blood, tissue, and health information from 15,000 people with and without heart conditions. The goal is to help researchers better understand diseases like aortic aneurysm, heart failure, and bicuspid aortic valve. Participants provide…

This study tests an AI software called Aorta AIM that automatically measures the aorta from CT scans. Researchers will compare its measurements to those of expert doctors using 250 existing scans from Brazil and the US. The goal is to see if the AI is accurate and can help doctor…

This study tests whether 3D printed models of a patient's diseased aorta can help surgeons plan aneurysm surgery better. Ten people with aortic aneurysms will have their CT scans turned into physical models for the surgeon to study before the operation. The main goal is to see if…

This study aims to understand how exercise affects the aorta in people with aortic aneurysm. Researchers will use special MRI scans during exercise to measure how the aorta stretches and responds. They will also test tissue samples from surgery to see how it relates to MRI findin…

This study is gathering 5,000 people with certain gene changes that raise the risk of aortic disease (like aneurysms or dissections). Researchers will track their health over time to see how these genes affect the condition. The goal is to better predict and manage the disease, n…

This study looks at the strength of the aorta (the main artery) in people having heart surgery. Researchers want to find out why some aortas are weak and prone to tearing or bursting. They will compare tissue from patients with aortic disease to those without. The goal is to bett…