ANATOMIC STAGE IV BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE IV BREAST CANCER AJCC V8 explained in plain language.
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Promising combo for rare breast cancer stalls after single patient
Disease control TerminatedThis study aimed to find a safe dose and see if combining dasatinib (a targeted cancer drug) with icosapent ethyl (an omega-3 fatty acid) could shrink tumors in people with a rare, aggressive form of breast cancer that had spread. Only one person enrolled before the study was sto…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 01:02 UTC
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Genetic testing guides cancer treatment in new study
Disease control TerminatedThis study tested a precision medicine approach for people with advanced cancers like breast, ovarian, pancreatic, prostate, or sarcoma. Researchers used genetic and protein tests to track how the cancer changes and then a team of experts recommended personalized drugs. The goal …
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated May 17, 2026 00:59 UTC
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Cancer brain metastasis drug combo trial halted early
Disease control TerminatedThis study tested two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the best dose and see if the combination could slow or stop tumor growth. The trial was stopped early after enrolling only 8 participants, so no clear…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug cocktails aim to shrink Hard-to-Treat breast tumors
Disease control TerminatedThis study tested several drug combinations in 24 people with metastatic triple-negative breast cancer, a type that has spread and is hard to treat. The drugs work by blocking cancer growth signals or boosting the immune system. The study was stopped early, so results are limited…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Gordon Mills, MD, PhD • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New combo therapy for rare breast cancer mutation shows promise in early trial
Disease control TerminatedThis study looked at adding a targeted drug (binimetinib) to standard hormone therapy (fulvestrant) for people with a certain genetic change (NF1) in advanced breast cancer. The goal was to see if the combination could shrink tumors or keep them from growing longer than the stand…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Promising combo trial for aggressive breast cancer halted early
Disease control TerminatedThis study looked at adding a drug called copanlisib to standard targeted therapy (trastuzumab and pertuzumab) for people with advanced HER2-positive breast cancer that has a specific genetic change (PIK3CA or PTEN mutation). The goal was to see if the combination could shrink tu…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Could meal timing protect your brain during cancer treatment?
Symptom relief TerminatedThis study tested a mobile app that helps people with brain metastases from breast or lung cancer follow a time-restricted eating plan. The goal was to see if changing when they eat could reduce memory and thinking problems after radiation therapy. Only one person enrolled before…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Antifungal drug explored as brain tumor treatment – study halted early
Knowledge-focused TerminatedThis study looked at whether the antifungal drug ketoconazole could block a protein called tGLI1 in brain tumors. It included 15 adults with breast cancer that spread to the brain or with a type of brain tumor called glioma. The goal was to see if the drug could affect the tumor'…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC