ALZHEIMER'S DISEASE (AD)

This study aims to improve how doctors detect early signs of Alzheimer's disease in people aged 60 and older. Researchers will provide general practitioners and specialists with digital cognitive tests and blood-based biomarkers to identify individuals with mild cognitive decline…

This study tests a medical device called Neuclare that is placed on the head to see if it can temporarily improve thinking and planning skills in people with mild cognitive impairment or very early Alzheimer's disease. About 138 adults aged 55 to 90 who are already on memory medi…

This observational study will follow 50,000 people with Alzheimer's or related dementias for many years, collecting medical information from routine doctor visits. Researchers hope to better understand how the disease progresses and how well treatments work in real life. Particip…

This study aims to validate a new serious game test called REALSoCog that helps detect social behavior problems in people with Alzheimer's disease, Lewy body dementia, or frontotemporal degeneration. Researchers will test 120 patients and their caregivers to see if the game can i…

This study explores better methods for running clinical trials in dementia and cognitive decline. Researchers will use a new measurement called 'δ' that combines thinking ability and daily function, along with blood protein levels, to see if they can predict who will respond to t…

This study tests a new PET imaging tracer to measure levels of a protein called Hsp90 in the brain. Hsp90 helps proteins fold correctly, and problems with this process are linked to Alzheimer's, Parkinson's, and ALS. Researchers will scan healthy volunteers and patients to see if…

This study is creating a large collection of information and biological samples from people with various neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's. Researchers will track changes in thinking, language, and brain imaging over time. The goal is to better und…

This study is testing a new 10-minute tool called CHRONOS to measure how people with Alzheimer's disease perceive time. Researchers want to see if problems with time perception can serve as early warning signs of cognitive decline. The study involves 40 participants and aims to i…

This study is testing whether a remotely delivered exercise and dementia care program is practical and helpful for older adults with Down syndrome (age 35+) and their caregivers. The goal is to see if people will join, stay in, and safely complete the 12-week program. It also loo…