Blood test could revolutionize Alzheimer's diagnosis, reducing need for spinal taps and scans
NCT ID NCT07680335
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study looks at whether measuring certain proteins in the blood (p-tau217 and neurofilament light) can help doctors diagnose Alzheimer's disease more quickly and confidently in people with memory problems. About 550 participants visiting a memory clinic will have their blood tested, and researchers will track how the results change the diagnosis and the doctor's certainty. The goal is to see if blood-based biomarkers can replace or reduce the need for more invasive or expensive tests like spinal taps or brain scans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Plasma p-tau217 and neurofilament light chain blood test
What this could lead to
If successful, this could make Alzheimer's diagnosis faster, less invasive, and more accessible, helping patients get the right care sooner.
What could go wrong
The study is observational and does not test a treatment. Blood tests may not be accurate enough in all cases, and results may not change how doctors manage patients.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood Test for Alzheimer's Diagnosis in Primary NCT07666113
- Pink Noise Brain Stimulation for Alzheimer's Mem NCT04570761
- Blood Biomarker Screening for Alzheimer's – NCT07570719
- 8M2D Alzheimer's Trial Safety Study (NCT07568041)
- Better Ways to Test Dementia Treatments - NCT05592678
- Alzheimer's rHSA Safety Study (NCT06489015)
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam UMC
RECRUITINGAmsterdam, North Holland, 1081HV, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Dijklander Ziekenhuis
RECRUITINGPurmerend, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Elisabeth-TweeSteden Ziekenhuis
NOT_YET_RECRUITINGTilburg, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Flevoziekenhuis
RECRUITINGAlmere Stad, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Frisius MC
RECRUITINGLeeuwarden, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Jeroen Bosch Ziekenhuis
RECRUITING's-Hertogenbosch, Netherlands
Contact Phone: •••-•••-••••
Contact
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Spaarne Gasthuis
RECRUITINGHaarlem, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Tergooi MC
RECRUITINGHilversum, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact