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Zapping the brain to boost memory and mood in Alzheimer's

NCT ID NCT07694921

ENROLLING_BY_INVITATION Symptom relief Sponsor: First Affiliated Hospital of Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study tests a non-invasive technique called temporal interference stimulation (TIS) that uses weak electrical fields to target deep brain areas involved in memory and emotion. Researchers will give two weeks of TIS to people with Alzheimer's disease who also have depression, then measure changes in thinking, mood, and brain activity. The goal is to see if this safe, painless method can improve both cognitive and emotional symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Temporal Interference Stimulation (TIS) device
What this could lead to
If it works, this could offer a drug-free way to ease both cognitive decline and depression in Alzheimer's patients.
What could go wrong
This is a small, early study with only 30 participants, so results may not apply widely. The treatment is experimental and its long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER'S DISEASE (AD)

Contacts and locations

Locations

  • Department of Psychiatry, First Affiliated Hospital of Zhejiang University

    Hangzhou, Zhejiang, 310000, China

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