ALZHEIMER DISEASE, EARLY ONSET
Clinical trials for ALZHEIMER DISEASE, EARLY ONSET explained in plain language.
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New Alzheimer's drug enters early human testing
Disease control Recruiting nowThis study is testing an experimental drug called DNL628 in people with early-stage Alzheimer's disease. The main goal is to see if the drug is safe and how the body processes it. About 68 participants will receive either DNL628 or a placebo. This is an early-phase trial, so it f…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: PHASE1 • Sponsor: Denali Therapeutics Inc. • Aim: Disease control
Last updated Jul 02, 2026 03:00 UTC
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New injection aims to tackle Alzheimer's at its roots
Disease control Recruiting nowThis study tests a new drug called ARO-MAPT-SC in healthy people and those with early Alzheimer's. The goal is to check if it is safe and how the body processes it. Participants receive either the drug or a placebo by injection under the skin. The trial is still in early stages, …
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: PHASE1, PHASE2 • Sponsor: Arrowhead Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Zapping the brain to fight Alzheimer's: new trial launches
Disease control Recruiting nowThis study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can slow cognitive decline in people with early Alzheimer's disease. The treatment targets a key brain region affected by Alzheimer's. Fifty-five partici…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: NA • Sponsor: Willem de Haan • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Could flickering lights and sounds slow Alzheimer's? MIT launches home device trial
Disease control Recruiting nowThis study tests whether a device that flashes light and plays sound at a specific frequency (40Hz) can help people with mild Alzheimer's. Sixty participants will use the device at home for an hour each day over six months. Researchers will check brain waves, memory, and blood ma…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: NA • Sponsor: Massachusetts Institute of Technology • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New Alzheimer's drug THN391 enters first patient trial
Disease control Recruiting nowThis study tests an experimental drug called THN391 in 15 people with early Alzheimer's disease who also have small vessel disease in the brain. Participants receive three monthly IV infusions of either THN391 or a placebo. The main goal is to check safety and how the drug behave…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: PHASE1 • Sponsor: Therini Bio, Inc. • Aim: Disease control
Last updated Jun 26, 2026 16:27 UTC
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Brain games and tai chi tested for Early-Onset Alzheimer's
Symptom relief Recruiting nowThis study is testing whether computerized brain training (BrainHQ) and Tai Chi-Qi Gong can improve memory, thinking, and mood in people with early-onset Alzheimer's disease. Sixty participants aged 40-64 will be assigned to either the training program or an active control group.…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a gentle brain zapping boost memory and mood in early dementia?
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called tDCS, combined with cognitive training, can improve thinking skills and mood in people with mild cognitive impairment or early dementia. Fifty participants will receive both real and placebo stimulation in…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: NA • Sponsor: University of Campania Luigi Vanvitelli • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Alzheimer's drug vs. brain exercises: which works better?
Symptom relief Recruiting nowThis study compares two approaches for treating newly diagnosed Alzheimer's disease: the drug donepezil versus a non-drug approach using cognitive stimulation or remediation. Researchers will measure changes in thinking and memory over 6 months in 240 participants aged 50 and old…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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New brain scan could spot Alzheimer's years earlier
Knowledge-focused Recruiting nowThis study tests a new, non-invasive MRI technique to detect early brain changes linked to Alzheimer's disease. Researchers will compare brain scans from 50 people with mild memory concerns to healthy volunteers. The goal is to find a simple, affordable way to identify those at r…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: NA • Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New brain scan method aims to spot Alzheimer's and Parkinson's early
Knowledge-focused Recruiting nowThis study is testing whether a new, low-cost type of brain scan can find early signs of Alzheimer's and Parkinson's disease. Researchers will compare brain scans from 120 people, including those at risk for Alzheimer's, those with Parkinson's, and healthy volunteers. The goal is…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase: NA • Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC