ALS
Clinical trials for ALS explained in plain language.
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New pill aims to slow ALS progression in early trial
Disease control Not yet recruitingThis study tests an oral drug called Kamlanoflast in 40 people with ALS. The goal is to see if it is safe, tolerable, and can reduce inflammation and slow decline in muscle function over 24 weeks. Participants must be 18-75 years old, diagnosed with ALS, and have had symptoms for…
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: Inflammasome Therapeutics • Aim: Disease control
Last updated May 11, 2026 20:49 UTC
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New ALS drug trial aims to slow disease progression
Disease control Not yet recruitingThis study tests a new drug, PLL001, in 153 adults with ALS (Lou Gehrig's disease). The goal is to see if it is safe and can slow the disease or improve survival. Participants will receive either the drug or a placebo daily for up to 24 weeks, with an option to continue longer.
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: PLL TX AUSTRALIA PTY LTD • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC
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New screening study aims to speed up ALS trial matching
Knowledge-focused Not yet recruitingThis study screens 500 people with ALS to see if they qualify for early-phase clinical trials. Participants undergo tests and provide blood samples to help match them to the right trial. The goal is to make trial enrollment faster and build a research database for future ALS stud…
Matched conditions: ALS
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 08:01 UTC
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Can your phone detect ALS decline? new study recruits spanish speakers
Knowledge-focused Not yet recruitingThis study will test whether a smartphone app can reliably measure speech and breathing changes in Spanish-speaking people with ALS. About 35 participants with ALS and a similar number of healthy volunteers will record speaking and breathing tasks over time. The goal is to develo…
Matched conditions: ALS
Sponsor: Nova Southeastern University • Aim: Knowledge-focused
Last updated May 17, 2026 08:00 UTC
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New PET tracer could reveal hidden brain inflammation in ALS
Knowledge-focused Not yet recruitingThis early-phase study tests a new radioactive tracer called [11C]CPPC for PET scans in 20 people with ALS and healthy volunteers. The goal is to see if the tracer can safely detect brain inflammation linked to ALS and track changes over time. This research aims to improve unders…
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC