ALS
Clinical trials for ALS explained in plain language.
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New daily shot aims to slow ALS
Disease control Not yet recruitingThis study tests a new drug, PLL001, in 153 people with ALS. It is given as a daily injection under the skin. The trial is split into two parts: first to check safety, then to see if it slows the disease and helps people live longer. Participants are randomly assigned to get eith…
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: PLL TX AUSTRALIA PTY LTD • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New ALS drug trial aims to tame inflammation
Disease control Not yet recruitingThis early-phase trial tests an oral drug, Kamlanoflast, in 40 people with ALS. Over 24 weeks, researchers will check safety, tolerability, and whether the drug reduces inflammation and slows decline in function. It is not yet recruiting.
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: Inflammasome Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New PET tracer aims to spot brain inflammation in ALS
Knowledge-focused Not yet recruitingThis early-phase study tests a special dye called [11C]CPPC used in PET scans to see if it can safely detect brain inflammation in people with ALS. Researchers will compare scans from 20 ALS patients and healthy volunteers to check if the dye highlights areas of inflammation and …
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can your phone detect ALS decline? new study aims to find out
Knowledge-focused Not yet recruitingThis study will enroll 35 Spanish-speaking adults with ALS and a similar group without ALS to see if a smartphone app can reliably measure changes in speech and breathing over time. Participants will use the app to record speaking and breathing tasks, and researchers will compare…
Matched conditions: ALS
Sponsor: Nova Southeastern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New ALS screening study aims to Fast-Track patients to trials
Knowledge-focused Not yet recruitingThis observational study screens 500 people with early-stage ALS to see if they qualify for specific early-phase clinical trials. Participants undergo tests, genetic analysis, and biomarker checks to match them with the right trial. The study also builds a research database for f…
Matched conditions: ALS
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC