ALS
Clinical trials for ALS explained in plain language.
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New hope for ALS: trial tests drug to slow devastating disease
Disease control Not yet recruitingThis study is testing a new drug called PLL001 for people recently diagnosed with ALS (Lou Gehrig's disease). The main goal is to see if daily injections can safely slow down the loss of physical function and improve survival. About 153 participants will receive either the real d…
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: PLL TX AUSTRALIA PTY LTD • Aim: Disease control
Last updated Apr 02, 2026 02:26 UTC
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New oral drug enters human testing for devastating ALS
Disease control Not yet recruitingThis early-stage study is testing a new oral drug called Kamlanoflast in 40 people with ALS (amyotrophic lateral sclerosis). The main goals are to check if the drug is safe and tolerable when taken for 24 weeks, and to see how it affects markers of inflammation and physical funct…
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: Inflammasome Therapeutics • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Mind-Controlled tech: brain implant trial offers hope for ALS independence
Disease control Not yet recruitingThis study is testing a brain implant called the Synchron BCI in people with ALS who have lost the use of both arms. The implant is designed to detect brain signals related to movement and translate them into commands to control digital devices, like computers. The main goal is t…
Matched conditions: ALS
Phase: NA • Sponsor: Synchron, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New program aims to match ALS patients with Cutting-Edge trials
Knowledge-focused Not yet recruitingThis study aims to identify people with ALS who might qualify for early-stage clinical trials. Participants will undergo health assessments and provide blood samples to check if they match specific trial requirements. The research also creates a database of genetic and health inf…
Matched conditions: ALS
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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New brain scan seeks to unlock clues in ALS
Knowledge-focused Not yet recruitingThis study is testing a new type of brain scan to see if it can detect inflammation in the brains of people with ALS. Researchers will compare scans from 20 people with ALS to scans from healthy people to see if the scan can spot differences linked to the disease. The main goal i…
Matched conditions: ALS
Phase: PHASE1, PHASE2 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Smartphone app aims to listen for early signs of ALS decline
Knowledge-focused Not yet recruitingThis study aims to understand how speech and breathing change over time in Spanish-speaking people with ALS. Researchers will use a smartphone app to record participants' speech and breathing tasks regularly. The goal is to see if these recordings can serve as reliable digital ma…
Matched conditions: ALS
Sponsor: Nova Southeastern University • Aim: Knowledge-focused
Last updated Mar 10, 2026 12:53 UTC