ALS

This study tested the long-term safety of an oral medication called edaravone for people with ALS (amyotrophic lateral sclerosis). The trial followed 185 adults with ALS for 24 to 48 weeks to see how well they tolerated the medication. The goal was to understand potential side ef…

This study followed patients who completed earlier trials of oral edaravone for ALS to monitor long-term safety. Fifteen participants in Japan took the medication in cycles until it became commercially available or until August 2023. The main goal was to track side effects and ad…

This study tested whether adding a new drug called IFB-088 to the standard medication riluzole could help people with a specific, rapidly progressing form of ALS that starts with speech and swallowing problems. 51 participants were randomly assigned to receive either IFB-088 or a…

This study tested whether a drug called PrimeC is safe and can help slow down ALS. For six months, 69 people with ALS took either PrimeC or a placebo pill twice daily, while continuing their standard ALS medications. Researchers checked for side effects and measured changes in ph…

This study tested whether a moderate-intensity breathing exercise program is safe and tolerable for people with ALS. Nine participants used a portable device at home to perform breathing exercises for 12 weeks, with most check-ins done via video calls. The main goal was to see if…

This study aimed to understand how nerve cells in the spinal cord communicate in ALS (amyotrophic lateral sclerosis). Researchers compared electrical activity in the spinal nerves of 101 healthy people and recently diagnosed ALS patients. The goal was to find measurable signs (bi…