ALCOHOL USE DISORDER (AUD)

This study tests a weekly injection called pemvidutide to see if it can reduce heavy drinking in adults with alcohol use disorder who are also overweight or obese. About 100 participants will receive either the drug or a placebo for 24 weeks. The main goal is to measure the chang…

This study tests whether a non-invasive ultrasound treatment can lower cravings and help prevent relapse in people with alcohol use disorder. Forty adults will receive either real or fake (sham) ultrasound to the brain. The goal is to see if this safe, painless method can reduce …

This study follows 120 people in group therapy for alcohol use disorder to see which patient traits—like mental health, drinking severity, personality, or thinking skills—lead to better outcomes. Researchers want to help doctors choose the right therapy for each person. The goal …

This study looks at how a single dose of a ketone ester supplement changes energy use in the brain and heart of people with alcohol use disorder compared to healthy volunteers. Twenty adults will receive either the supplement or a placebo and then have PET/CT scans to measure glu…

This study looks at whether giving non-alcoholic beers to people being treated for alcohol use disorder is acceptable and practical. About 60 adults in California who are already in a treatment program will receive non-alcoholic beers for 6 weeks. Researchers will measure satisfa…