Ketone drink may reveal hidden link between brain and heart in alcohol addiction

NCT ID NCT05015881

First seen Apr 10, 2026 · Last updated May 01, 2026 · Updated 3 times

Summary

This study looks at how a single dose of a ketone ester supplement changes the way the brain and heart use sugar for energy in people with alcohol use disorder compared to healthy volunteers. Twenty adults aged 21 to 65 will receive either the supplement or a placebo, then have a special PET/CT scan to measure glucose activity. The goal is to better understand the relationship between brain and heart function in alcohol dependence.

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Contacts and locations

Locations

  • University of Pennsylvania Center for Studies of Addiction

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.