ADVANCED RENAL CELL CARCINOMA
Clinical trials for ADVANCED RENAL CELL CARCINOMA explained in plain language.
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Promising combo targets bone metastases in advanced kidney cancer
Disease control OngoingThis study tests whether adding a radioactive drug (radium-223) to the standard treatment (cabozantinib) can improve outcomes for people with advanced kidney cancer that has spread to the bone. About 134 participants will receive either the combination or cabozantinib alone. The …
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 00:47 UTC
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New combo therapy targets Hard-to-Treat kidney cancer
Disease control OngoingThis study tests whether combining two drugs—nivolumab and a radioactive antibody called 177Lu-girentuximab—is safe and effective for people with advanced clear cell kidney cancer that has a specific protein (CAIX). Nine participants will receive the treatment to find the best do…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New combo therapy under Real-World watch for advanced kidney cancer
Disease control OngoingThis study tracks adults with advanced kidney cancer who are receiving a combination of two drugs, cabozantinib and nivolumab, as their first treatment. Researchers are observing how long patients live and how long the cancer stays under control in everyday medical practice. The …
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Sponsor: Ipsen • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug duo aims to outsmart advanced kidney cancer
Disease control TerminatedThis study tests whether a new combination of immunotherapy drugs (botensilimab and balstilimab) works better than the current standard treatment for advanced kidney cancer. About 120 people with untreated metastatic clear cell renal cell carcinoma will take part. The goal is to …
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Michael B. Atkins, MD • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Gut bacteria boosts cancer therapy? new combo trial for kidney cancer
Disease control OngoingThis early-phase study tests whether adding a gut bacteria supplement (CBM588) to standard cancer drugs (nivolumab and cabozantinib) can improve treatment for advanced kidney cancer. About 31 adults with metastatic kidney cancer will take the supplement alongside their regular th…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New combo therapy shows promise for HIV patients with advanced cancer
Disease control OngoingThis early-phase trial is testing the safety of combining two cancer drugs—nivolumab and cabozantinib—in people with HIV who have advanced solid tumors. The study includes 8 participants with various cancers that have spread. The goal is to see if the combination can shrink or st…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Biopsy study aims to match advanced cancer patients with best treatments
Knowledge-focused OngoingThis study collects tissue and blood samples from 156 people with advanced prostate, kidney, or bladder cancers. Researchers analyze these samples to find genetic markers that predict how well different treatments work. Participants undergo a biopsy of a growing tumor before star…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Kidney cancer drug study: real patients, real side effects
Knowledge-focused OngoingThis study watches 224 adults with advanced kidney cancer who are already taking cabozantinib (alone or with nivolumab) as their first treatment. Researchers track how often patients need to lower doses, pause, or stop treatment due to side effects. No new drugs are tested; the g…
Matched conditions: ADVANCED RENAL CELL CARCINOMA
Sponsor: Ipsen • Aim: Knowledge-focused
Last updated Apr 26, 2026 19:36 UTC