ADVANCED MELANOMA
Clinical trials for ADVANCED MELANOMA explained in plain language.
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Melanoma combo therapy study halted early
Disease control TerminatedThis study tested a new combination treatment for people with advanced melanoma that cannot be removed by surgery or has spread. The combination included an experimental drug injected into tumors (CMP-001) plus an immunotherapy given through a vein (nivolumab). It was compared to…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE2, PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Experimental melanoma cocktail trial halted early
Disease control TerminatedThis early-stage trial tested a combination of an experimental fusion protein (hu14.18-IL2), radiation, and two immunotherapy drugs (nivolumab and ipilimumab) in people with advanced melanoma that couldn't be surgically removed. The goal was to find the safest dose and check for …
Matched conditions: ADVANCED MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Experimental triple therapy for advanced cancers shows early promise but trial halted
Disease control TerminatedThis early-phase trial tested the drug plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combination was safe and could shrink…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Cheaper cancer drug copy tested in melanoma trial – but study halted early
Disease control TerminatedThis study tested a biosimilar (JPB898) against the original immunotherapy Opdivo, both combined with Yervoy, in 52 adults with advanced melanoma that could not be surgically removed. The goal was to see if the biosimilar works just as well. However, the trial was terminated earl…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE3 • Sponsor: Sandoz • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Gut bacteria boosts cancer drug? early trial hints at possibility
Disease control TerminatedThis study tested whether taking a pill containing gut bacteria (EDP1503) could help the immunotherapy drug pembrolizumab (Keytruda) work better in people with advanced melanoma. The trial included two groups: those who had never received anti-PD1 therapy and those whose cancer h…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Experimental tumor injection trial halted early
Disease control TerminatedThis early-stage trial tested an experimental drug called SAR441000, injected directly into tumors, either alone or with another drug (cemiplimab) given through a vein. The study aimed to find a safe dose and see if the combination could shrink tumors in people with advanced soli…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE1 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 26, 2026 15:44 UTC