ADVANCED MELANOMA
Clinical trials for ADVANCED MELANOMA explained in plain language.
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New combo therapy takes on advanced cancers
Disease control Not yet recruitingThis early-stage study tests a new drug called N-3C01, given alone or with an immunotherapy, in people with advanced solid tumors that have spread or cannot be removed. The main goals are to check safety, find the right dose, and see if the combination shrinks tumors. About 114 a…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Hefei Xinzhu Biological Technology Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Could a common diabetes drug boost immunotherapy in Hard-to-Treat cancers?
Disease control Not yet recruitingThis early-phase trial is testing whether adding sitagliptin, a diabetes drug, to the immunotherapy pembrolizumab is safe and can help people with advanced kidney cancer or melanoma whose cancer has stopped responding to standard treatment. The study will first find the safest do…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE1 • Sponsor: Fernando Maciel Barbosa • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Could the time of day you get immunotherapy boost its power against melanoma?
Disease control Not yet recruitingThis study looks at whether giving immunotherapy infusions in the morning improves outcomes for people with advanced melanoma. Researchers will compare morning versus afternoon/evening dosing in 108 participants. The goal is to see if aligning treatment with the body's natural im…
Matched conditions: ADVANCED MELANOMA
Phase: PHASE4 • Sponsor: Swiss Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Personalized cell therapy takes on advanced melanoma in new trial
Disease control Not yet recruitingThis Phase 2 trial tests whether a personalized cell therapy called HS-IT101 works better than chemotherapy for people with advanced melanoma that has stopped responding to standard treatments. HS-IT101 uses a patient's own immune cells, grown in large numbers in a lab, to fight …
Matched conditions: ADVANCED MELANOMA
Phase: PHASE2 • Sponsor: Qingdao Sino-Cell Biomedicine Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Fasting during immunotherapy: a new way to boost treatment?
Symptom relief Not yet recruitingThis study looks at whether intermittent fasting is safe and doable for people with advanced solid tumors who are starting immunotherapy. About 90 participants will be split into three groups: no fasting, eating only during an 8-hour window each day, or fasting every other day. R…
Matched conditions: ADVANCED MELANOMA
Phase: NA • Sponsor: West Virginia University • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Fitbit and app aim to catch immunotherapy side effects early
Symptom relief Not yet recruitingThis study tests whether a digital tool combining weekly symptom surveys and a Fitbit can help monitor patients during immunotherapy for advanced melanoma. Forty participants will be randomly assigned to use the tool or receive usual care. The goal is to see if the system is easy…
Matched conditions: ADVANCED MELANOMA
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC