ADULT

This study tests whether an investigational drug called HF1K16, when combined with the approved drug bevacizumab, can help people with recurrent or progressive glioma—a type of brain tumor. The trial enrolls about 30 adults whose tumors have returned or worsened after prior treat…

This early-phase study tests a combination of a specially modified virus (PIN) and an immunotherapy drug (sintilimab) in about 25 adults with advanced colorectal cancer that has spread to the liver and has not responded to at least two prior treatments. The main goals are to chec…

This study will test a new imaging agent called 68Ga-B6FA-01, which targets two different markers on cancer cells and their surroundings. The goal is to see if this probe can improve PET/CT scans for diagnosing and staging solid tumors. About 100 adults with newly diagnosed or re…

This study tests a 5-day program called LasaiOn that combines mild nerve stimulation with breathing exercises to help adults feel less stressed and anxious. Researchers will measure changes in mood, heart rate, and brain activity in 200 participants. The goal is to see if this sa…

This study tests whether an instructional video about medication management can reduce errors in kidney transplant patients compared to standard verbal instructions. About 308 adult patients at Erasmus MC will be randomly assigned to watch the video or receive usual teaching. Res…

This study will compare the effects of free weight exercises (like dumbbells and barbells) versus weight machines on muscle strength and endurance. Twenty-six inactive adults aged 18-30 will be assigned to one of two groups and train three times a week for eight weeks. The goal i…

This study will give 180 healthy adults a daily probiotic supplement (Lactobacillus plantarum) for 1 or 6 months. Researchers will collect blood and stool samples and run online cognitive tests to see if the supplement changes gut bacteria, blood markers, or thinking skills. The …

This study looks at a protein called I-FABP, which is released when gut cells are damaged. Researchers will measure it in the blood and urine of 500 ICU patients to see if it relates to how severe their gastrointestinal problems are. No treatments are given—this is purely to gath…

This study will follow 500 critically ill adults in the ICU to see if changes in a blood protein called prealbumin can predict who will die or get infections. Researchers will track prealbumin levels over time and compare them to patient outcomes. No new treatment is given—partic…