ACUTE LYMPHOID LEUKEMIA
Clinical trials for ACUTE LYMPHOID LEUKEMIA explained in plain language.
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New stem cell therapy aims to tame transplant complications
Disease control OngoingThis study tests a new treatment called Orca-T for people with advanced blood cancers like leukemia. It uses a special mix of stem cells and immune cells from a donor to help the body accept the transplant while reducing serious side effects like graft-versus-host disease. The go…
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Phase: PHASE1 • Sponsor: Orca Biosystems, Inc. • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Targeted drug aims to clear hidden leukemia before transplant
Disease control OngoingThis study tests whether the targeted drug inotuzumab ozogamicin can eliminate minimal residual disease (MRD) in adults with B-cell acute lymphoblastic leukemia (ALL) before they receive a stem cell transplant. Participants have either Philadelphia chromosome-positive or -negativ…
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Phase: PHASE2 • Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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New transplant approach aims to tame Graft-Versus-Host disease
Disease control OngoingThis early-phase study tests a stem cell transplant method for people with advanced blood cancers like leukemia. Instead of using strong drugs to prevent complications, doctors give specially selected immune cells (regulatory T-cells) along with regular T-cells to help the body a…
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Phase: PHASE1 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New engineered graft aims to improve stem cell transplants for kids with leukemia
Disease control TerminatedThis study tests a specially engineered donor graft called Orca-Q in children and young adults with blood cancers who need a stem cell transplant. The graft is designed to help the new cells take hold and reduce complications. The trial is currently on hold, but aims to enroll 40…
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New stem cell mix aims to make transplants safer for blood cancer patients
Disease control OngoingThis phase 3 trial tests a new treatment called Orca-T for people with advanced blood cancers like leukemia. Orca-T is a special mix of stem cells and immune cells from a matched donor, designed to reduce a serious side effect called graft-versus-host disease. The study compares …
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Phase: PHASE3 • Sponsor: Orca Biosystems, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New hope for leukemia patients allergic to key chemo drug
Disease control NO_LONGER_AVAILABLEThis study offers Erwinase, a different form of chemotherapy, to children and adults with acute lymphoblastic leukemia (ALL) who have had allergic reactions to standard L-asparaginase drugs. The goal is to provide a safe treatment option for those who cannot use the usual medicat…
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Sponsor: Phoenix Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New cord blood treatment shows promise for tough leukemia cases
Disease control OngoingThis phase II trial tests a new way to use cord blood transplants for people with high-risk acute leukemia or myelodysplasia. The cord blood is treated with a molecule called UM171 to increase the number of stem cells, which may help the transplant work better and reduce serious …
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Phase: PHASE2 • Sponsor: Ciusss de L'Est de l'Île de Montréal • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Could muscle loss predict blood cancer outcomes?
Knowledge-focused OngoingThis study is investigating how common muscle loss, known as sarcopenia, is in people with blood cancers like leukemia, lymphoma, and myeloma. Researchers will measure body composition using DXA scans and track hospital stays, disease progression, and survival. The goal is to see…
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Muscle weakness may predict transplant success in blood cancer patients
Knowledge-focused OngoingThis study follows 144 blood cancer patients undergoing stem cell transplants to see how muscle function changes and whether it predicts complications like infections, relapse, or survival. Researchers will measure muscle mass and track medical events over time. The goal is to un…
Matched conditions: ACUTE LYMPHOID LEUKEMIA
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC