New stem cell therapy aims to cut transplant complications in blood cancer patients
NCT ID NCT05316701
First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 38 times
Summary
This phase 3 trial tests a new treatment called Orca-T for people with advanced blood cancers like leukemia. Orca-T uses a special mix of stem cells and immune cells from a matched donor to help the body accept the transplant and reduce serious side effects. The study compares Orca-T to standard stem cell transplants in 187 patients to see if it improves survival without severe graft-versus-host disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope
Duarte, California, 91010, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Colorado Blood Cancer Institute
Denver, Colorado, 80218, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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OU Health Stephenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
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Oregon Health & Sciences University - Knight Cancer Institute
Portland, Oregon, 97239, United States
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Ronald Reagan UCLA Medical Center
Los Angeles, California, 90095, United States
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Sarah Cannon Research Institute
Nashville, Tennessee, 37239, United States
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Stanford Health Care
Stanford, California, 94305, United States
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UC Davis
Sacramento, California, 95817, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Miami Hospital and Clinics - Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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University of Michigan Health System - Michigan Medicine
Ann Arbor, Michigan, 48109, United States
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University of Utah
Salt Lake City, Utah, 84112, United States
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Vanderbilt University
Nashville, Tennessee, 37232, United States
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Weill Cornell Medicine - New York-Presbyterian Hospital
New York, New York, 10021, United States
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Winship Cancer Institute - Emory University
Atlanta, Georgia, 30322, United States
Conditions
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