Zygomycosis

This study tested the safety and effectiveness of the antifungal drug isavuconazole as a first treatment for Chinese patients with serious invasive fungal infections caused by Aspergillus or other molds. All 70 participants received the drug for up to 84 days (or 180 days for cer…

This study tested whether the antifungal drug posaconazole (taken as a pill) works as well as the standard IV drug amphotericin B for treating a serious lung infection called pulmonary mucormycosis. The trial involved 82 adults with this rare but deadly infection. Researchers com…

This study looked at how safe and effective the drug Cresemba (isavuconazole) is for Korean patients with serious fungal infections like invasive aspergillosis or mucormycosis. Researchers tracked side effects and how well the drug worked in 94 adults. The goal was to confirm the…

This Phase 2 trial tested a high dose (10 mg/kg/day) of the antifungal drug liposomal amphotericin B (Ambisome) in 40 people with zygomycosis, a rare but serious fungal infection. The goal was to see if the high dose could effectively control the infection after 4 weeks of treatm…

This study looked back at 60 adult blood cancer patients who had stem cell transplants and later developed a rare fungal infection called mucormycosis. Researchers compared cases before COVID-19 (2015-2020) to during the pandemic (2020-2024) to see if the virus, new tests, or new…

This completed study looked at medical records of 307 adults in five European countries who were treated with the antifungal drug isavuconazole for serious fungal infections (invasive aspergillosis or mucormycosis). Researchers tracked how well the drug worked (clinical, radiolog…