X-linked nonsyndromic hearing loss
MONDO:0019586X-linked form of nonsyndromic deafness.
Also known as: X-linked isolated neurosensory hearing loss type DFN, X-linked isolated sensorineural hearing loss type DFN, X-linked non-syndromic neurosensory hearing loss type DFN, X-linked non-syndromic sensorineural hearing loss type DFN, X-linked deafness, X-linked isolated neurosensory deafness type DFN, X-linked isolated sensorineural deafness type DFN, X-linked non-syndromic neurosensory deafness type DFN
81 clinical trials for this condition and its sub-types.
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Broader categories
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New cochlear implant aims to help those with partial hearing hear better
Disease control CompletedThis study tested a new cochlear implant (CI632) in 10 adults who have some low-frequency hearing but poor high-frequency hearing. The goal was to see if the implant improves speech understanding and overall hearing. Participants received the implant and were followed to measure …
Phase: NA • Sponsor: Cochlear • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Brain wave test could revolutionize hearing checks for children
Diagnosis CompletedThis study tested a new method called CORGEE that uses brain wave recordings (EEG) to measure how well children with hearing loss understand speech. Unlike standard hearing tests that require kids to respond verbally, this approach is objective and does not need active participat…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Diagnosis
Last updated Jun 26, 2026 15:12 UTC
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New device may help seniors with cochlear implants hear in crowded rooms
Symptom relief CompletedThis study tested a device that sends sound from the non-hearing ear to a cochlear implant in the other ear. 16 older adults with one cochlear implant used the device to see if it improved their speech understanding in noisy settings. The goal was to also see if it improved quali…
Phase: NA • Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Teletherapy for deaf kids: a new way to bridge language gaps?
Symptom relief CompletedThis study tested whether speech-language teletherapy can improve language outcomes in deaf or hard-of-hearing children aged 0-27 months. Researchers enrolled 210 children, some publicly insured and some privately insured, and gave some access to an 18-month teletherapy program. …
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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New minimally invasive ear implant surgery shows promise for hearing loss
Symptom relief CompletedThis study tested a new, less invasive surgical method for placing a bone-anchored hearing device (Ponto implant) in 52 adults with hearing loss. The goal was to see if the implant stayed securely in place without causing skin problems or pain. The approach aims to make the proce…
Phase: NA • Sponsor: Oticon Medical • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Can a simple supplement quiet tinnitus and save your hearing?
Symptom relief CompletedThis study tested a daily dietary supplement called ACEMg (Soundbites) in 64 adults with hearing loss or tinnitus. Participants took the supplement for 24 weeks and completed hearing tests and symptom surveys at home using a smartphone app. The goal was to see if the supplement c…
Phase: NA • Sponsor: Keep Hearing, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Acupuncture meets modern medicine: can a herb injection ease hearing loss and vertigo?
Symptom relief CompletedThis completed study tested whether adding gastrodin acupoint injections to standard care helps people with sudden hearing loss and vertigo. One hundred adults received either standard therapy alone or standard therapy plus injections into specific acupuncture points over four we…
Phase: NA • Sponsor: The First Hospital of Hebei Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New app aims to sharpen listening skills for hearing aid users
Symptom relief CompletedThis study tested the ALICE app, a smartphone tool designed to train listening and communication skills in people with hearing loss. 161 adults who already use hearing aids or cochlear implants used the app alongside their usual care. The goal was to see if the app could improve …
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Hearing aid hidden in your glasses? new study puts it to the test
Symptom relief CompletedThis completed study tested Nuance Audio glasses, which have a built-in hearing aid for adults with mild to moderate hearing trouble. 21 participants wore the glasses and took speech tests in quiet and noisy settings, plus a real-world walking tour. The goal was to see if the dev…
Phase: NA • Sponsor: Luxottica Group S.p.A. • Aim: Symptom relief
Last updated Jun 26, 2026 13:43 UTC
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Scientists hunt for genes behind inner ear malformation
Knowledge-focused CompletedThis study looked at 324 people with hearing loss and an inner ear problem called enlarged vestibular aqueducts. Researchers collected DNA, hearing tests, and scans to find genes that may cause the condition. The goal was to learn more about why it happens, not to test a treatmen…
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Scientists hunt for genes behind hearing loss and dizziness
Knowledge-focused CompletedThis study aims to find the genetic causes of hereditary hearing loss and balance disorders. Researchers will study families with these conditions, collecting medical history, blood or cheek swabs, hearing and balance tests, and sometimes scans. The goal is to identify genes and …
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Smart software could help cochlear implant users hear better
Knowledge-focused CompletedThis study tested whether a computer model could find the best combination of active electrodes in a cochlear implant to improve speech understanding. Fourteen adults with cochlear implants tried different settings, including ones recommended by the model, and their speech recogn…
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Simple signs and amplifiers may cut hospital delirium
Knowledge-focused CompletedThis study looked at whether hearing and vision loss are linked to delirium (sudden confusion) in older hospital patients. Over 1,500 participants answered screening questions and had their hearing and vision tested. In a smaller trial, researchers tested if posting communication…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New program aims to boost mental toughness in Hearing-Impaired students
Knowledge-focused CompletedThis study tested a program designed to improve psychological hardiness (like resilience and commitment) in hard-of-hearing female students in Saudi Arabia. 25 students took part, with some receiving the program and others continuing their usual activities. The goal was to see if…
Phase: NA • Sponsor: King Faisal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New study explores smarter ways for deaf children to build vocabulary
Knowledge-focused CompletedThis study looked at whether using feedback and spacing out practice sessions can help children aged 5 to 9 who are deaf or hard of hearing learn new words more efficiently. Thirteen children took part in word-learning exercises to see which methods worked best. The goal was to f…
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Inner ear secrets: study aims to predict who will hear better with hearing aids
Knowledge-focused CompletedThis completed study enrolled 186 people with mild to moderate hearing loss to understand how damage to inner ear sensory cells and auditory neurons affects speech understanding, especially in noisy environments. Participants were fitted with hearing aids and tested on speech rec…
Sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Eye-Tracking study reveals how kids read lips – app may boost skills
Knowledge-focused CompletedThis study looked at how children with and without hearing loss use eye gaze and facial expressions to improve speechreading (lip-reading). Researchers tested 140 children aged 8–11 with cognitive and speechreading tasks, and some children with hearing loss trained using a specia…
Phase: NA • Sponsor: University of Oulu • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Cochlear implant users train with music to boost hearing and enjoyment
Knowledge-focused CompletedThis study looked at whether musical pitch training can improve music appreciation and hearing in people with cochlear implants. 120 teenage and adult implant users took part, with some receiving musical training and others visual training as a comparison. The goal was to underst…
Phase: NA • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Scientists aim to tune cochlear implants without patient feedback
Knowledge-focused CompletedThis study looked at 49 adult cochlear implant users to see if electrical measurements from the inner ear can predict the best sound levels for each person. Researchers collected data during surgery and after months of implant use, then compared it to standard hearing tests. The …
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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French hearing aid questionnaires get a scientific Check-Up
Knowledge-focused CompletedThis study tested whether French versions of two standard hearing aid benefit questionnaires (IOI-HA and COSI) are accurate and reliable. Researchers enrolled 100 adults with hearing loss who use hearing aids. The goal was to confirm these questionnaires work well in French, so c…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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App could help cochlear implant users hear better in noisy places
Knowledge-focused CompletedThis study tested a mobile app that lets adults with cochlear implants track their hearing difficulties in real-world situations, like noisy restaurants. The goal was to see if the app could collect useful data on how the implant performs outside the clinic. Fifty-one experienced…
Phase: NA • Sponsor: Cochlear • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Wider hearing implant holds up after a decade, study finds
Knowledge-focused CompletedThis study followed 51 adults who received a wider bone-anchored hearing implant (BIA300) to see how well it stayed in place and worked after 10 years. Researchers measured implant stability and checked for any skin or tissue problems. The goal was to see if the wider design is a…
Phase: NA • Sponsor: Radboud University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Virtual reality training aims to sharpen sound location skills in deaf patients
Knowledge-focused CompletedThis completed study tested whether a virtual reality training program could improve the ability to locate sounds in people with hearing loss. 79 participants performed sound localization tasks with and without visual feedback. The goal was to see if training could reduce pointin…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:38 UTC