Venous insufficiency
MONDO:0000945Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with edema and sometimes with venous stasis ulcers at the ankle.
Also known as: venous insufficiency, venous insufficiency (disease), peripheral venous insufficiency
101 clinical trials for this condition and its sub-types, 50 tagged with Venous insufficiency itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Venous insufficiency
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Chronic venous insufficiency 59 trials
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Post-thrombotic syndrome 13 trials
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Glue vs. heat vs. knife: which vein fix wins?
Disease control Stopped earlyThis study tested a medical glue called VenaSeal against heat therapy or surgery for treating venous reflux, a condition where leg veins don't pump blood properly. About 500 adults with early to advanced vein disease took part. The goal was to see which method patients liked more…
Sponsor: Medtronic Endovascular • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Varicose vein treatment showdown: foam vs. heat
Symptom relief Stopped earlyThis study compared two treatments for varicose veins: Varithena (a foam) and Endothermal Ablation (using heat). It included 43 adults with a faulty great saphenous vein. The goal was to see which treatment better reduced symptoms like heaviness and pain over 3 months.
Phase 4 • Sponsor: Boston Scientific Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New wound pump shows promise for stubborn leg ulcers
Symptom relief Stopped earlyThis study tested whether a single-use negative pressure wound therapy system (PICO) helps heal hard-to-treat venous leg ulcers better than standard care. About 142 adults with leg ulcers that had lasted at least 6 weeks took part. The main goal was to see if more ulcers healed c…
Sponsor: Smith & Nephew, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC