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Thrombotic disease
MONDO:0000831The formation of a blood clot in the lumen of a vessel or heart chamber; causes include coagulation disorders and vascular endothelial injury.
Also known as: Clots, blood, Thromboses, blood Clots, blood clot, clot, blood, thrombosis, thrombotic disorder, thrombus
332 clinical trials for this condition and its sub-types.
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Broader categories
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Weekly Finger-Prick test may keep elderly patients safer on blood thinners
Disease control TerminatedThis study tested whether checking blood clotting levels every week with a small finger-prick device is better than the usual monthly lab test for elderly nursing home residents on blood thinners. The goal was to see which method keeps patients in the safe therapeutic range longe…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Experimental drug aims to restore platelets in Heparin-Triggered disorder
Disease control TerminatedThis study tested an experimental drug called VLX-1005 in people with a rare condition where the blood thinner heparin causes a dangerous drop in platelets (cells that help blood clot). Participants received either VLX-1005 or a placebo alongside standard care. The goal was to se…
Phase: PHASE2 • Sponsor: Veralox Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Simple blood test may predict Post-Surgery clot risk
Knowledge-focused TerminatedThis pilot study aimed to see if a blood test called thromboelastography (TEG) and platelet mapping could predict clotting or bleeding complications after non-cardiac surgery. The study included 200 patients who were taking aspirin or clopidogrel for at least 10 days before elect…
Sponsor: McMaster University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused TerminatedThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase: PHASE4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Scientists investigate tiny blood particles to improve burn recovery
Knowledge-focused TerminatedThis study looked at how blood clotting and inflammation change over time in adults with serious burns. Researchers examined tiny particles released by cells into the blood, which may play a role in infections and inflammation. The goal was to learn how to reduce bleeding, transf…
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New scan could help doctors plan better liver cancer treatments
Knowledge-focused TerminatedThis study tested a special type of scan (SPECT/CT) to see how well it measures liver function in people with liver cancer who are getting radiation or surgery. The goal was to learn if this scan can help doctors see which parts of the liver are working well before, during, and a…
Phase: NA • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC