Experimental drug for heparin-triggered blood disorder tested, but study stopped early

NCT ID NCT05785819

First seen Jan 06, 2026 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tested a new drug called VLX-1005 for a rare condition where the blood thinner heparin causes low platelet counts and dangerous blood clots. About 24 adults with suspected heparin-induced thrombocytopenia were randomly assigned to receive either VLX-1005 or a placebo, on top of standard care. The goal was to see if the drug helped platelet levels recover faster and prevented complications like strokes or clots. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Carilion Medical Center

    Roanoke, Virginia, 24014, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • MedStar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Universiy of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Versiti at Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Yale University

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.