Experimental drug aims to restore platelets in Heparin-Triggered disorder
NCT ID NCT05785819
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested an experimental drug called VLX-1005 in people with a rare condition where the blood thinner heparin causes a dangerous drop in platelets (cells that help blood clot). Participants received either VLX-1005 or a placebo alongside standard care. The goal was to see if the drug could help platelet levels recover faster and prevent complications like blood clots or stroke. The study was stopped early, so results are limited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Contacts and locations
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Locations
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Carilion Medical Center
Roanoke, Virginia, 24014, United States
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Duke University
Durham, North Carolina, 27710, United States
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Georgetown University
Washington D.C., District of Columbia, 20007, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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Stanford University
Stanford, California, 94305, United States
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Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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University of Colorado
Aurora, Colorado, 80045, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Washington
Seattle, Washington, 98195, United States
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Universiy of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Versiti at Froedtert Hospital
Milwaukee, Wisconsin, 53226, United States
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Yale University
New Haven, Connecticut, 06510, United States