Stiff-person syndrome
MONDO:0008491Stiff-man syndrome (SMS) is a rare neurological disorder comprising fluctuating trunk and limb stiffness, painful muscle spasms, task-specific phobia, an exaggerated startle response, and ankylosing deformities such as fixed lumbar hyperlordosis.
Also known as: Moersch-Woltman syndrome, Stiff Person Syndrome, Stiff Person syndrome, Stiff-man syndrome, stiff-person syndrome, Morsch Woltman syndrome, SMS, SPS
12 clinical trials for this condition and its sub-types.
Follow this condition to get notified about new trialsSub-types
Broader categories
-
Can a simple blood test unlock the secrets of brain autoimmune diseases?
Knowledge-focused Recruiting nowThis study aims to discover biological markers (biomarkers) that could help doctors diagnose and track neurological autoimmune diseases such as multiple sclerosis, myasthenia gravis, and Guillain-Barre syndrome. Researchers will analyze samples from 50,000 people, including patie…
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
-
CAR T-Cell therapy: what happens years later?
Knowledge-focused Recruiting nowThis study follows about 70 people who have already received KYV-101, a CAR T-cell therapy, for autoimmune diseases like lupus and multiple sclerosis. Researchers will monitor participants for up to 15 years to track any delayed side effects, new cancers, or other health problems…
Sponsor: Kyverna Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC