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Staphylococcal toxic-shock syndrome

MONDO:0020545

Staphylococcal toxic shock syndrome (staphylococcal TSS) is an acute disease mediated by the production of superantigenic toxins, characterized by high fever, skin rash followed by skin peeling, hypotension, vomiting, diarrhea and potentially leading to multisystem organ failure and caused by a Staphylococcus aureus bacterial infection.

Also known as: Staphylococcus caused toxic shock syndrome, Staphylococcus toxic shock syndrome, staphylococcal TSS

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Infectious disease (282) Toxic shock syndrome (206) Bacterial infectious disease (93) Staphylococcal infection (38) Syndromic disease (25) Human disease (14) Commensal bacterial infectious disease (0) Disease by body system or component (0) Disease by etiologic mechanism (0)
Trials to join now! 1 Completed 1
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  • Can immune antibodies fight toxic shock in kids? small trial hopes to find out

    Disease control Completed

    This study tested whether giving intravenous immunoglobulin (IVIG) to children with toxic shock syndrome is practical and might help. Toxic shock is a rare but life-threatening reaction to bacterial toxins. The trial enrolled 30 children in intensive care, giving them either IVIG…

    Phase: PHASE2 • Sponsor: Hospices Civils de Lyon • Aim: Disease control

    Last updated Jun 26, 2026 14:21 UTC

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