Spontaneous intracranial hypotension

This study tests a procedure called transvenous embolization to treat spontaneous intracranial hypotension, a condition where spinal fluid leaks cause severe headaches. Researchers at Mayo Clinic will enroll 200 people with confirmed CSF-venous fistulas. The goal is to see if blo…

This study tests whether placing a small tube (stent) in a narrowed brain vein works better than standard medication for people with idiopathic intracranial hypertension (high pressure in the brain). About 74 adults with this condition and a narrowed vein will be randomly assigne…

This study compares two types of CT myelography scans to detect CSF-venous fistulas, abnormal connections that cause spinal fluid leaks, in 200 adults with spontaneous intracranial hypotension (low-pressure headaches). Participants will be randomly assigned to receive either a ne…

This study tests whether inserting a tiny needle into the ear and applying a mild electrical current (called percutaneous needle electrolysis) can help people with frequent headaches. Researchers will use an infrared camera to measure changes in facial skin temperature, since peo…

This study looks at whether a nerve block in the back of the head can temporarily relieve severe headaches caused by a spinal fluid leak. About 34 adults with this condition will receive the injection and be monitored for pain changes. The goal is to provide a safe, accessible br…

This study is testing whether a non-invasive eye scan called optical coherence tomography (OCT) can help track neurological diseases like multiple sclerosis, Alzheimer's, Parkinson's, and migraine. Over two years, researchers will measure the thickness of retinal layers in 840 pa…