Spinal injury

This trial tests whether using a patient-specific 3D-printed model of the spine helps surgeons plan screw placement for thoracic or lumbar fractures. Sixteen people with a single broken vertebra will be split into two groups: one using standard CT scans for planning, the other us…

This study tests whether a non-invasive technique called transcutaneous spinal electrical stimulation (TSES) can improve how well people with spinal cord injury respond to exercise. Participants will do cycling-like leg exercises with and without TSES to see if it boosts oxygen u…

This study tests whether pouring tranexamic acid (TXA), a drug that helps blood clot, directly into the surgical wound during spine surgery can reduce bleeding and the need for blood transfusions. About 252 adults with spinal injuries or deformities will be randomly assigned to r…

This study looks at how well a spine implant (VIPER PRIME/Expedium) combined with a special bone graft putty (Fibergraft BG) helps bones fuse together after spine surgery. About 100 adults with spine problems like slipped vertebrae or disc degeneration will be followed for two ye…

This study tests whether adding robot-assisted arm and hand exercises to standard occupational therapy helps people with cervical spinal cord injury regain upper-limb function. Thirty participants will be randomly assigned to receive either standard therapy alone or standard ther…

This study tests whether a gentle, non-invasive device placed on the ear can help reduce pain after lumbar (lower back) surgery. The device stimulates nerves in the ear to change how the brain processes pain. Researchers will enroll 20 adults having back surgery to see if this ap…

This study will follow 1,000 people receiving Medtronic spinal or cranial devices during routine surgery. Researchers will track outcomes like fusion success, pain relief, and device safety for up to two years. The goal is to gather real-world data on how these already-approved p…

This study tests whether a set of simple decision rules, adapted from the Canadian C-Spine Rule, can help emergency responders decide when a neck collar and hospital imaging are truly needed. Researchers will enroll 840 stable, conscious adults with recent neck trauma treated by …

This study is tracking 561 people who have already had spine surgery using METROSAN spinal implants and BONEGRAFT bone fillers. Researchers want to see how well these devices work and if any new safety issues pop up over a year. It's an observational study, meaning patients get s…

This study looks at whether wearing a rigid neck collar is needed for stable neck fractures. About 616 adults with these fractures will be treated either with a collar for 12 weeks or without one. The goal is to see if both approaches lead to similar healing, while avoiding colla…

This study is developing a decision tool to help doctors identify blunt trauma patients who can safely skip abdominal-pelvic CT scans, avoiding unnecessary radiation and expense. Researchers will collect data from 12,000 patients in the emergency department to find a set of clini…

This study uses advanced MRI scans to look at changes in the spinal cord and fluid around it in people with spinal cord injuries. The goal is to see if these changes relate to a person's symptoms and nerve function. Researchers hope this will lead to earlier diagnosis and better …