Speech disorder
MONDO:0004730A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders.
Also known as: speech impediment or impairment
80 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Brain implant aims to give voice to those trapped in silence
Disease control Not yet recruitingThis study tests a fully wireless brain-computer interface (BCI) that aims to decode attempted speech in real time for people with locked-in syndrome (LIS), often caused by ALS or stroke. The implant records brain signals from areas controlling the mouth and throat, then translat…
Phase: NA • Sponsor: University Hospital, Grenoble • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Mind-Reading chip aims to give voice to the speechless
Disease control Not yet recruitingThis early study tests a small, wireless brain implant designed to help people with severe speech problems communicate by thought. Four adults with conditions like locked-in syndrome or ALS will get the implant and learn to control it. The main goal is to see if the device is saf…
Phase: NA • Sponsor: Shanghai StairMed Technology Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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A Drug-Free tongue workout may help people speak more clearly
Symptom relief Not yet recruitingThis trial tests whether a two-week tongue-strengthening exercise, done with a non-invasive device, can improve speech fluency in people with tongue-tie or slurred speech. The exercise relies on muscle resistance training, not medication or electronics. Researchers will measure c…
Phase: NA • Sponsor: Dream Video LLC • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Tongue tied? how posture could unlock clearer speech in kids
Symptom relief Not yet recruitingThis study looks at whether posture and tongue position affect how children pronounce Hebrew sounds. Researchers will test if adding muscle-strengthening exercises to regular speech therapy helps kids learn correct pronunciation faster. About 80 children with and without speech i…
Phase: NA • Sponsor: University of Haifa • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Can an AI app fix Kids' speech delays? new trial aims to find out
Symptom relief Not yet recruitingThis study tests whether an AI-based app called HiDongDong can improve speech in children aged 2 to 14 who have trouble pronouncing words. Forty-eight children will either use the app at home for 20 minutes a day, five days a week, or receive standard speech therapy. The goal is …
Phase: NA • Sponsor: Seoul National University Bundang Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Magic mushroom compound could help people who stutter
Symptom relief Not yet recruitingThis Phase 2 pilot study will test whether a single high dose of psilocybin (the active ingredient in magic mushrooms) combined with speech therapy can improve fluency and reduce struggle in 25 adults who stutter. Researchers will measure changes in stuttering severity and brain …
Phase: PHASE2 • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Olive oil and xylitol mouth rinse may shield cancer patients from painful mouth sores
Knowledge-focused Not yet recruitingThis study looks back at the medical records of 60 adults with head and neck cancer who received radiation therapy, with or without chemotherapy, and used a topical mouth rinse made from olive oil, betaine, and xylitol. The goal is to see how often severe mouth sores (oral mucosi…
Sponsor: Mucosa Innovations, S.L. • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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Jaw surgery for sleep apnea may cause temporary speech issues, study finds
Knowledge-focused Not yet recruitingThis study looks at how often people develop speech or swallowing problems after a jaw-advancement surgery for obstructive sleep apnea. Researchers will measure nasality, speech, and swallowing in 28 adults before and after surgery at five different times. The goal is to better u…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New study aims to predict speech delays in kids with autism
Knowledge-focused Not yet recruitingThis study will follow 120 Mandarin-speaking children with autism and typically developing children to understand how speech develops over time. Researchers will use parent reports and play sessions to track language skills. The goal is to create models that help predict speech p…
Sponsor: Children's Hospital of Chongqing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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AI vs. experts: can a computer judge speech as well as a human?
Knowledge-focused Not yet recruitingThis study will compare how well an AI program (Blings) measures speech clarity in 40 adults with speech disorders from stroke or other neurological conditions. Two speech therapists will also rate the same speech samples. The goal is to see if the AI can reliably replace or assi…
Sponsor: Pusan National University Yangsan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC