Sclerosteosis
MONDO:0017838Sclerosteosis is a very rare serious sclerosing hyperostosis syndrome characterized clinically by variable syndactyly and progressive skeletal overgrowth (particularly of the skull), resulting in distinctive facial features (mandibular overgrowth, frontal bossing, midfacial hypoplasia), cranial nerve entrapment causing facial palsy and deafness, and potentially lethal elevation of intracranial pressure.
Also known as: cortical hyperostosis with syndactyly, cortical hyperostosis-syndactyly syndrome
5 clinical trials for this condition and its sub-types.
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Broader categories
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Dialysis upgrade could protect bones in kidney patients
Disease control Not yet recruitingThis study tests whether a newer type of dialysis filter (medium cut-off membrane) can better manage bone and mineral problems common in people with end-stage kidney disease. Thirty adults on maintenance dialysis will try both the new and standard filters for three months each. R…
Phase: NA • Sponsor: Gazi University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Dialysis showdown: which method protects heart and bones best?
Knowledge-focused Not yet recruitingThis study looks at how different types of dialysis affect heart health, bone metabolism, inflammation, and quality of life in people with end-stage kidney disease. Researchers will compare patients on hemodialysis, continuous ambulatory peritoneal dialysis, and automated periton…
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC