Schizotypal personality disorder
MONDO:0001087A disorder characterized by an enduring pattern of inability to establish close relationships coupled with cognitive or perceptual distortions, odd beliefs and speech, and eccentric behavior and appearance.
27 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Drugs and therapy together: a new hope for anxiety, depression, and more?
Disease control CompletedThis early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disord…
Phase: PHASE1 • Sponsor: Rakitzi, Stavroula • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Can two antipsychotics together tame schizophrenia better?
Disease control CompletedThis study looked at 6 people with schizophrenia who were already taking a combination of two long-acting injectable medications: Abilify Maintena and Rexulti. Researchers tracked their symptoms and side effects over 6 months to see how well the combo worked in everyday life. The…
Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Can talk therapy cut crime risk in people with personality disorders?
Disease control CompletedThis study looked at whether schema therapy, a type of talk therapy, can help people with personality disorders who are in outpatient forensic care. Five participants received therapy for up to two years. Researchers measured changes in their thinking patterns, risk of re-offendi…
Phase: NA • Sponsor: Vrije Universiteit Brussel • Aim: Disease control
Last updated Jun 26, 2026 19:11 UTC
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Can virtual reality help quiet paranoia in schizophrenia?
Symptom relief CompletedThis trial tests whether adding virtual reality to cognitive behavioural therapy (CBT) can better reduce persecutory thoughts in people with schizophrenia spectrum disorders compared to traditional CBT alone. About 256 participants will receive either VR-assisted CBT or standard …
Phase: NA • Sponsor: Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital • Aim: Symptom relief
Last updated Aug 14, 2026 00:00 UTC
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Caregiver support program shows promise for families facing eating disorders
Symptom relief CompletedThis study tested a program called Family Connections for caregivers of people with both an eating disorder and a personality disorder. The goal was to see if the program could reduce stress and conflict at home. 124 Spanish caregivers took part, and researchers measured things l…
Phase: NA • Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Smartphone apps show promise for schizophrenia symptom management
Symptom relief CompletedThis study tested two mobile health (mHealth) strategies to help people with schizophrenia manage their symptoms. 299 participants used smartphone tools to track and improve issues like depression, anxiety, and insomnia. The goal was to see if these digital tools could make a rea…
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Could VR help sharpen your mind? new study tests brain training in virtual reality
Symptom relief CompletedThis study tested whether a 4-week virtual reality (VR) training program could improve thinking skills in 62 people with depression, bipolar disorder, or psychotic disorders like schizophrenia. Participants practiced daily-life tasks in VR, such as cooking and shopping, guided by…
Phase: NA • Sponsor: Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New pilot study aims to help people with psychosis in africa through peer support and community resources
Knowledge-focused CompletedThis pilot study tested a community-based intervention for people with psychosis in Malawi, Nigeria, Sierra Leone, and Zimbabwe. The program includes peer support from someone who has experienced psychosis, case management, and help with daily activities like finding work or soci…
Phase: NA • Sponsor: London School of Hygiene and Tropical Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC