Rheumatoid factor-negative juvenile idiopathic arthritis
MONDO:0019432Rheumatoid factor-negative polyarthritis is a term used to describe a group of poorly defined heterogenous conditions that incorporates forms of rheumatoid factor-negative polyarthritis and forms of oligoarticular arthritis that become extensive in less than 6 months after onset.
Also known as: juvenile rheumatoid factor-negative polyarthritis, polyarthritis without rheumatoid factor, rheumatoid factor-negative JIA
26 clinical trials for this condition and its sub-types.
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Broader categories
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A short therapy program may help workers with arthritis keep their jobs — a trial puts it to the test
Disease control CompletedThis trial tests whether a brief vocational rehabilitation program can help people with arthritis who are worried about losing their jobs. Participants, all currently employed and living or working in eastern Massachusetts, will work with a physical or occupational therapist to i…
Phase: NA • Sponsor: Boston University Charles River Campus • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Hip resurfacing device shows promise in arthritis patients
Disease control CompletedThis study looked at the long-term safety and effectiveness of the Birmingham Hip Resurfacing System, a metal hip implant, in 329 adults with arthritis. The main goal was to see how many patients needed a revision (replacement or removal) within 10 years. The study also measured …
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Kids with quiet arthritis may taper meds without Flare-Ups, study finds
Disease control CompletedThis study looked at 62 children with juvenile idiopathic arthritis whose disease was inactive. Researchers tested whether slowly reducing and then stopping their biologic medication was as safe and effective as staying on the full dose for 24 weeks. The goal was to see if taperi…
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Knee implant study shows good function after two years
Disease control CompletedThis study looked at how well a specific knee replacement (balanSys UNI) works over time. 116 people with knee arthritis got the implant and were followed for at least 2 years. Doctors measured knee function using the Knee Society Score and checked X-rays for any problems.
Sponsor: Mathys Ltd Bettlach • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Stretching your way to better hips? pilot study tests the idea
Symptom relief CompletedThis pilot study looked at whether passive static stretching can increase hip flexibility in three groups: people who had hip replacement, those with long-term hip pain, and healthy volunteers. Twelve participants followed a 4-week stretching program three times a week under supe…
Sponsor: Omicron beta research • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Robot-Assisted knee surgery may outperform traditional methods
Symptom relief CompletedThis study compared robotic-assisted total knee replacement to the conventional technique in 95 patients with knee arthritis. The goal was to see if robotic surgery leads to better knee function, less pain, and higher satisfaction two years after the operation. Researchers also c…
Phase: NA • Sponsor: Hospital de Terrassa • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Scientists analyze genetic markers in stored samples to boost personalized medicine
Knowledge-focused CompletedThis study looked at DNA methylation patterns in stored samples from 90 patients with rare skeletal disorders, sarcomas, or inflammatory arthritis. The goal was to better understand these patterns and explore their potential for diagnosis and treatment. The research aimed to impr…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Can a simple question curb doctor bias? new study tests individuation in rheumatology
Knowledge-focused CompletedThis completed pilot study tested whether training doctors to ask personalized questions (individuation) could improve care for Black and lower-income patients with rheumatic diseases like lupus and arthritis. Over 200 patients and their rheumatologists took part. The goal was to…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Knee implant showdown: which design stays put?
Knowledge-focused CompletedThis study looked at two different designs of knee replacement implants in 60 people with arthritis. The goal was to see how much each implant moved inside the bone over two years using a special X-ray technique called RSA. The findings could help surgeons pick the better implant…
Phase: NA • Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:07 UTC